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Chen C, Hu J, Zeng P, Pan F, Yaseen M, Xu H, Lu JR. Molecular mechanisms ofanticancer action and cell selectivity of short α-helical peptides. Biomaterials.2014 Feb;35(5):1552-61. doi: 10.1016/j.biomaterials.2013.10.082. Epub 2013 Nov15. 24246647
Pennarun B, Gaidos G, Bucur O, Tinari A, Rupasinghe C, Jin T, Dewar R, Song K,Santos MT, Malorni W, Mierke D, Khosravi-Far R. killerFLIP: a novel lytic peptidespecifically inducing cancer cell death. Cell Death Dis. 2013 Oct 31;e894. doi:10.1038/cddis.2013.401. 24176852
Hsiao YC, Wang KS, Tsai SH, Chao WT, Lung FD. Anticancer activities of anantimicrobial peptide derivative of Ixosin-B amide. Bioorg Med Chem Lett. 2013Oct 15;23(20):5744-7. doi: 10.1016/j.bmcl.2013.07.063. Epub 2013 Aug 9. 23993331
Gross S, Wilms D, Krause J, Brezesinski G, Andrä J. Design of NK-2-derivedpeptides with improved activity against equine sarcoid cells. J Pept Sci. 2013Oct;19(10):619-28. doi: 10.1002/psc.2540. Epub 2013 Jul 25. 23893605
Guo X, Ma C, Du Q, Wei R, Wang L, Zhou M, Chen T, Shaw C. Two peptides, TsAP-1and TsAP-2, from the venom of the Brazilian yellow scorpion, Tityus serrulatus:evaluation of their antimicrobial and anticancer activities. Biochimie. 2013Sep;95(9):1784-94. doi: 10.1016/j.biochi.2013.06.003. Epub 2013 Jun 14. 23770440
Ortuso F, Paduano F, Carotenuto A, Gomez-Monterrey I, Bilotta A, Gaudio E,Sala M, Artese A, Vernieri E, Dattilo V, Iuliano R, Brancaccio D, Bertamino A,Musella S, Alcaro S, Grieco P, Perrotti N, Croce CM, Novellino E, Fusco A,Campiglia P, Trapasso F. Discovery of PTPRJ agonist peptides that effectivelyinhibit in vitro cancer cell proliferation and tube formation. ACS Chem Biol.2013 Jul 19;8(7):1497-506. doi: 10.1021/cb3007192. Epub 2013 May 13. 23627474
Lin MC, Hui CF, Chen JY, Wu JL. Truncated antimicrobial peptides from marineorganisms retain anticancer activity and antibacterial activity againstmultidrug-resistant Staphylococcus aureus. Peptides. 2013 Jun;139-48. doi:10.1016/j.peptides.2013.04.004. Epub 2013 Apr 15. 23598079
Wang C, Zhou Y, Li S, Li H, Tian L, Wang H, Shang D. Anticancer mechanisms of temporin-1CEa, an amphipathic α-helical antimicrobial peptide, in Bcap-37 humanbreast cancer cells. Life Sci. 2013 May 30;92(20-21):1004-14. doi:10.1016/j.lfs.2013.03.016. Epub 2013 Apr 10. 23583573
Wang C, Tian LL, Li S, Li HB, Zhou Y, Wang H, Yang QZ, Ma LJ, Shang DJ. Rapid cytotoxicity of antimicrobial peptide tempoprin-1CEa in breast cancer cellsthrough membrane destruction and intracellular calcium mechanism. PLoS One.2013;8(4):e60462. doi: 10.1371/journal.pone.0060462. Epub 2013 Apr 5. 23577112
Pepe G, Tenore GC, Mastrocinque R, Stusio P, Campiglia P. Potentialanticarcinogenic peptides from bovine milk. J Amino Acids. 2013;20939804. doi:10.1155/2013/939804. Epub 2013 Feb 26. 23533710
Nasrolahi Shirazi A, Tiwari R, Chhikara BS, Mandal D, Parang K. Design andbiological evaluation of cell-penetrating peptide-doxorubicin conjugates asprodrugs. Mol Pharm. 2013 Feb 4;10(2):488-99. doi: 10.1021/mp3004034. Epub 2013Jan 15. 23301519
Chen Y, Jiang S, Jin Y, Yin Y, Yu G, Lan X, Cui M, Liang Y, Wong BH, Guo L,Sun H. Purification and characterization of an antitumor protein withdeoxyribonuclease activity from edible mushroom Agrocybe aegerita. Mol Nutr Food Res. 2012 Nov;56(11):1729-38. doi: 10.1002/mnfr.201200316. Epub 2012 Oct 4. 23034893
van Zoggel H, Carpentier G, Dos Santos C, Hamma-Kourbali Y, Courty J, Amiche M, Delbé J. Antitumor and angiostatic activities of the antimicrobial peptidedermaseptin B2. PLoS One. 2012;7(9):e44351. doi: 10.1371/journal.pone.0044351.Epub 2012 Sep 20. 23028527
Alileche A, Goswami J, Bourland W, Davis M, Hampikian G. Nullomer derivedanticancer peptides (NulloPs): differential lethal effects on normal and cancercells in vitro. Peptides. 2012 Dec;38(2):302-11. doi:10.1016/j.peptides.2012.09.015. Epub 2012 Sep 20. 23000474
Liu JJ, Zhang BF, Yin XX, Pei DS, Yang ZX, Di JH, Chen FF, Li HZ, Xu W, WuYP, Zheng JN. Expression, purification, and characterization of RGD-mda-7, aHis-tagged mda-7/IL-24 mutant protein. J Immunoassay Immunochem.2012;33(4):352-68. doi: 10.1080/15321819.2012.659782. 22963485
Chen L, Patrone N, Liang JF. Peptide self-assembly on cell membranes toinduce cell lysis. Biomacromolecules. 2012 Oct 8;13(10):3327-33. doi:10.1021/bm301106p. Epub 2012 Sep 11. 22934601
Tørfoss V, Isaksson J, Ausbacher D, Brandsdal BO, Flaten GE, Anderssen T,Cavalcanti-Jacobsen Cde A, Havelkova M, Nguyen LT, Vogel HJ, Strøm MB. Improvedanticancer potency by head-to-tail cyclization of short cationic anticancerpeptides containing a lipophilic β(2,2) -amino acid. J Pept Sci. 2012Oct;18(10):609-19. doi: 10.1002/psc.2441. Epub 2012 Aug 30. 22933412
Won A, Ruscito A, Ianoul A. Imaging the membrane lytic activity of bioactive peptide latarcin 2a. Biochim Biophys Acta. 2012 Dec;1818(12):3072-80. doi:10.1016/j.bbamem.2012.07.030. Epub 2012 Aug 3. 22885172
Ausbacher D, Svineng G, Hansen T, Strøm MB. Anticancer mechanisms of actionof two small amphipathic β(2,2)-amino acid derivatives derived from antimicrobialpeptides. Biochim Biophys Acta. 2012 Nov;1818(11):2917-25. doi:10.1016/j.bbamem.2012.07.005. Epub 2012 Jul 20. 22820149
Lee MO, Kim EH, Jang HJ, Park MN, Woo HJ, Han JY, Womack JE. Effects of asingle nucleotide polymorphism in the chicken NK-lysin gene on antimicrobialactivity and cytotoxicity of cancer cells. Proc Natl Acad Sci U S A. 2012 Jul24;109(30):12087-92. doi: 10.1073/pnas.1209161109. Epub 2012 Jul 10. 22783018
Kang SJ, Ji HY, Lee BJ. Anticancer activity of undecapeptide analoguesderived from antimicrobial peptide, brevinin-1EMa. Arch Pharm Res. 2012May;35(5):791-9. doi: 10.1007/s12272-012-0505-0. Epub 2012 May 29. 22644847
Diao Y, Han W, Zhao H, Zhu S, Liu X, Feng X, Gu J, Yao C, Liu S, Sun C, PanF. Designed synthetic analogs of the α-helical peptide temporin-La with improved antitumor efficacies via charge modification and incorporation of the integrinαvβ3 homing domain. J Pept Sci. 2012 Jul;18(7):476-86. doi: 10.1002/psc.2420.Epub 2012 May 28. 22641352
Yu Y, Gao S, Li Q, Wang C, Lai X, Chen X, Wang R, Di J, Li T, Wang W, Wu X.The FGF2-binding peptide P7 inhibits melanoma growth in vitro and in vivo. JCancer Res Clin Oncol. 2012 Aug;138(8):1321-8. doi: 10.1007/s00432-012-1201-7.Epub 2012 Apr 6. 22481251
Nguyen GK, Lim WH, Nguyen PQ, Tam JP. Novel cyclotides and uncyclotides with highly shortened precursors from Chassalia chartacea and effects of methionineoxidation on bioactivities. J Biol Chem. 2012 May 18;287(21):17598-607. doi:10.1074/jbc.M111.338970. Epub 2012 Mar 30. 22467870
Sinthuvanich C, Veiga AS, Gupta K, Gaspar D, Blumenthal R, Schneider JP.Anticancer β-hairpin peptides: membrane-induced folding triggers activity. J AmChem Soc. 2012 Apr 11;134(14):6210-7. doi: 10.1021/ja210569f. Epub 2012 Mar 28. 22413859
Feng XL, Liu QT, Cao RB, Zhou B, Ma ZY, Deng WL, Wei JC, Qiu YF, Wang FQ, Gu JY, Wang FJ, Zheng QS, Ishag H, Chen PY. Identification and characterization ofnovel immunomodulatory bursal-derived pentapeptide-II (BPP-II). J Biol Chem. 2012Feb 3;287(6):3798-807. doi: 10.1074/jbc.M111.273854. Epub 2011 Dec 19. 22184121
Slaninová J, Mlsová V, Kroupová H, Alán L, Tůmová T, Monincová L, BorovičkováL, Fučík V, Ceřovský V. Toxicity study of antimicrobial peptides from wild beevenom and their analogs toward mammalian normal and cancer cells. Peptides. 2012 Jan;33(1):18-26. doi: 10.1016/j.peptides.2011.11.002. Epub 2011 Nov 7. 22100226
Yang L, Horibe T, Kohno M, Haramoto M, Ohara K, Puri RK, Kawakami K.Targeting interleukin-4 receptor α with hybrid peptide for effective cancertherapy. Mol Cancer Ther. 2012 Jan;11(1):235-43. doi:10.1158/1535-7163.MCT-11-0363. Epub 2011 Nov 14. 22084165
Miklán Z, Orbán E, Bánóczi Z, Hudecz F. New pemetrexed-peptide conjugates:synthesis, characterization and in vitro cytostatic effect on non-small cell lungcarcinoma (NCI-H358) and human leukemia (HL-60) cells. J Pept Sci. 2011Dec;17(12):805-11. doi: 10.1002/psc.1407. 22076954
Hilchie AL, Doucette CD, Pinto DM, Patrzykat A, Douglas S, Hoskin DW.Pleurocidin-family cationic antimicrobial peptides are cytolytic for breastcarcinoma cells and prevent growth of tumor xenografts. Breast Cancer Res. 2011Oct 24;13(5):R102. doi: 10.1186/bcr3043. 22023734
Gritzapis AD, Voutsas IF, Baxevanis CN. Ontak reduces the immunosuppressivetumor environment and enhances successful therapeutic vaccination inHER-2/neu-tolerant mice. Cancer Immunol Immunother. 2012 Mar;61(3):397-407. doi: 10.1007/s00262-011-1113-4. Epub 2011 Sep 18. 21928125
Mandal SM, Migliolo L, Das S, Mandal M, Franco OL, Hazra TK. Identificationand characterization of a bactericidal and proapoptotic peptide from Cycasrevoluta seeds with DNA binding properties. J Cell Biochem. 2012Jan;113(1):184-93. doi: 10.1002/jcb.23343. 21882228
Kawamoto M, Horibe T, Kohno M, Kawakami K. A novel transferrinreceptor-targeted hybrid peptide disintegrates cancer cell membrane to inducerapid killing of cancer cells. BMC Cancer. 2011 Aug 18;359. doi:10.1186/1471-2407-11-359. 21849092
He W, Chan LY, Zeng G, Daly NL, Craik DJ, Tan N. Isolation andcharacterization of cytotoxic cyclotides from Viola philippica. Peptides. 2011Aug;32(8):1719-23. doi: 10.1016/j.peptides.2011.06.016. Epub 2011 Jun 23. 21723349
Koszałka P, Kamysz E, Wejda M, Kamysz W, Bigda J. Antitumor activity ofantimicrobial peptides against U937 histiocytic cell line. Acta Biochim Pol.2011;58(1):111-7. Epub 2011 Mar 14. 21403917
Ohara K, Horibe T, Kohno M, Kawakami K. Characterization of antilytic peptideantibody: application for the detection of lytic-based hybrid peptide in serumsamples. J Pept Sci. 2011 Jul;17(7):493-8. doi: 10.1002/psc.1349. Epub 2011 Feb24. 21351323
Huang YB, Wang XF, Wang HY, Liu Y, Chen Y. Studies on mechanism of action of anticancer peptides by modulation of hydrophobicity within a defined structuralframework. Mol Cancer Ther. 2011 Mar;10(3):416-26. doi:10.1158/1535-7163.MCT-10-0811. Epub 2011 Jan 20. 21252288
Matsuo AL, Tanaka AS, Juliano MA, Rodrigues EG, Travassos LR. A novelmelanoma-targeting peptide screened by phage display exhibits antitumor activity.J Mol Med (Berl). 2010 Dec;88(12):1255-64. doi: 10.1007/s00109-010-0671-9. Epub2010 Aug 28. 20802991
Jin X, Mei H, Li X, Ma Y, Zeng AH, Wang Y, Lu X, Chu F, Wu Q, Zhu J.Apoptosis-inducing activity of the antimicrobial peptide cecropin of Muscadomestica in human hepatocellular carcinoma cell line BEL-7402 and the possiblemechanism. Acta Biochim Biophys Sin (Shanghai). 2010 Apr;42(4):259-65. 20383464
Smolarczyk R, Cichoń T, Kamysz W, Głowala-Kosińska M, Szydło A, Szultka L,Sieroń AL, Szala S. Anticancer effects of CAMEL peptide. Lab Invest. 2010Jun;90(6):940-52. doi: 10.1038/labinvest.2010.58. Epub 2010 Mar 8. 20212453
Monincová L, Budesínský M, Slaninová J, Hovorka O, Cvacka J, Voburka Z, FucíkV, Borovicková L, Bednárová L, Straka J, Cerovský V. Novel antimicrobial peptidesfrom the venom of the eusocial bee Halictus sexcinctus (Hymenoptera: Halictidae) and their analogs. Amino Acids. 2010 Aug;39(3):763-75. doi:10.1007/s00726-010-0519-1. Epub 2010 Mar 3. 20198492
Huang W, Lu L, Shao X, Tang C, Zhao X. Anti-melanoma activity of hybridpeptide P18 and its mechanism of action. Biotechnol Lett. 2010 Apr;32(4):463-9.doi: 10.1007/s10529-009-0175-2. Epub 2009 Dec 3. 19957017
Lu J, Chen ZW. Isolation, characterization and anti-cancer activity of SK84, a novel glycine-rich antimicrobial peptide from Drosophila virilis. Peptides.2010 Jan;31(1):44-50. doi: 10.1016/j.peptides.2009.09.028. Epub 2009 Sep 30. 19799950
Cerovský V, Budesínský M, Hovorka O, Cvacka J, Voburka Z, Slaninová J,Borovicková L, Fucík V, Bednárová L, Votruba I, Straka J. Lasioglossins: threenovel antimicrobial peptides from the venom of the eusocial bee Lasioglossumlaticeps (Hymenoptera: Halictidae). Chembiochem. 2009 Aug 17;10(12):2089-99. doi:10.1002/cbic.200900133. 19591185
Fadnes B, Rekdal O, Uhlin-Hansen L. The anticancer activity of lytic peptidesis inhibited by heparan sulfate on the surface of the tumor cells. BMC Cancer.2009 Jun 15;183. doi: 10.1186/1471-2407-9-183. 19527490
Shang D, Yu F, Li J, Zheng J, Zhang L, Li Y. Molecular cloning of cDNAsencoding antimicrobial peptide precursors from the skin of the Chinese brownfrog, Rana chensinensis. Zoolog Sci. 2009 Mar;26(3):220-6. doi:10.2108/zsj.26.220. 19341344
Conlon JM, Ahmed E, Coquet L, Jouenne T, Leprince J, Vaudry H, King JD.Peptides with potent cytolytic activity from the skin secretions of the NorthAmerican leopard frogs, Lithobates blairi and Lithobates yavapaiensis. Toxicon.2009 Jun;53(7-8):699-705. doi: 10.1016/j.toxicon.2009.02.018. Epub 2009 Feb 28. 19254736
Bowne WB, Sookraj KA, Vishnevetsky M, Adler V, Sarafraz-Yazdi E, Lou S,Koenke J, Shteyler V, Ikram K, Harding M, Bluth MH, Ng M, Brandt-Rauf PW, Hannan R, Bradu S, Zenilman ME, Michl J, Pincus MR. The penetratin sequence in theanticancer PNC-28 peptide causes tumor cell necrosis rather than apoptosis ofhuman pancreatic cancer cells. Ann Surg Oncol. 2008 Dec;15(12):3588-600. doi:10.1245/s10434-008-0147-0. Epub 2008 Oct 18. 18931881
Yang ST, Kim JI, Shin SY. Effect of dimerization of a beta-turn antimicrobialpeptide, PST13-RK, on antimicrobial activity and mammalian cell toxicity.Biotechnol Lett. 2009 Feb;31(2):233-7. doi: 10.1007/s10529-008-9848-5. Epub 2008 Sep 25. 18815734
Lee HS, Park CB, Kim JM, Jang SA, Park IY, Kim MS, Cho JH, Kim SC. Mechanism of anticancer activity of buforin IIb, a histone H2A-derived peptide. CancerLett. 2008 Nov 18;271(1):47-55. doi: 10.1016/j.canlet.2008.05.041. Epub 2008 Jul 9. 18617323
Onishi J, Roy MK, Juneja LR, Watanabe Y, Tamai Y. A lactoferrin-derivedpeptide with cationic residues concentrated in a region of its helical structure induces necrotic cell death in a leukemic cell line (HL-60). J Pept Sci. 2008Sep;14(9):1032-8. doi: 10.1002/psc.1039. 18425992
Suttmann H, Retz M, Paulsen F, Harder J, Zwergel U, Kamradt J, Wullich B,Unteregger G, Stöckle M, Lehmann J. Antimicrobial peptides of the Cecropin-familyshow potent antitumor activity against bladder cancer cells. BMC Urol. 2008 Mar3;5. doi: 10.1186/1471-2490-8-5. 18315881
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Prasad S, Mathur A, Jaggi M, Mukherjee R. Delivering multiple anticancerpeptides as a single prodrug using lysyl-lysine as a facile linker. J Pept Sci.2007 Jul;13(7):458-67. 17559067
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