Total number of Results for 293T are 132
ASPsiRNA ID Pairing of target region (top) and ASP-siRNA (bottom) Efficacy (mut)(%) Efficacy (wt) (%) Diff Gene Disease Mutation RefSNP Analysis Pubmed ID
ASPsiRNA ID Mutant allele/ASP-siRNA Efficacy
for mutant(%)		 Efficacy
for wild (%)		 Relative Difference (%) Gene Disease Mutation RefSNP Analysis Pubmed ID
aspsirna0274 UGCCA---GCUGUGGUCGGGCU
ACGGU---CGACACCAGCCCGA		 78 23 55 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0275 GUGCCA---GCUGUGGUCGGGC
CACGGU---CGACACCAGCCCG		 76 35 41 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0276 UGUGCCA---GCUGUGGUCGGG
ACACGGU---CGACACCAGCCC		 67 39 28 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0277 GUGUGCCA---GCUGUGGUCGG
CACACGGU---CGACACCAGCC		 66 20 46 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0278 GGUGUGCCA---GCUGUGGUCG
CCACACGGU---CGACACCAGC		 58 38 20 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0279 UGGUGUGCCA---GCUGUGGUC
ACCACACGGU---CGACACCAG		 60 43 17 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0280 CUGGUGUGCCA---GCUGUGGU
GACCACACGGU---CGACACCA		 80 45 35 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0281 CCUGGUGUGCCA---GCUGUGG
GGACCACACGGU---CGACACC		 70 40 30 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0282 CCCUGGUGUGCCA---GCUGUG
GGGACCACACGGU---CGACAC		 90 32 58 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0283 GCCCUGGUGUGCCA---GCUGU
CGGGACCACACGGU---CGACA		 24 0 24 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0284 AGCCCUGGUGUGCCA---GCUG
UCGGGACCACACGGU---CGAC		 90 43 47 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0285 GAGCCCUGGUGUGCCA---GCU
CUCGGGACCACACGGU---CGA		 88 21 67 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0286 GGAGCCCUGGUGUGCCA---GC
CCUCGGGACCACACGGU---CG		 30 18 12 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0287 CCA---GCUGUGGUCGGGCUCC
GGU---CGACACCAGCCCGAGG		 78 42 36 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0288 GCCA---GCUGUGGUCGGGCUC
CGGU---CGACACCAGCCCGAG		 67 40 27 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0289 UGCCA---GCUGUGGUCGGGCU
ACGGU---CGACACCAGCCCGA		 NA 70 NA COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0290 GUGUGCCA---GCUGUGGUCGG
CACACGGU---CGACACCAGCC		 NA 0 NA COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0291 UGGUGUGCCA---GCUGUGGUC
ACCACACGGU---CGACACCAG		 95 38 57 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0292 GGUGUGCCA---GCUGUGGUCG
CCACACGGU---CGACACCAGC		 80 38 42 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0293 UGUGCCA---GCUGUGGUCGGG
ACACGGU---CGACACCAGCCC		 90 34 56 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0294 GCCCUGGUGUGCCA---GCUGU
CGGGACCACACGGU---CGACA		 90 83 7 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0295 UGCCA---GCUGUGGUCGGGCU
ACGGU---CGACACCAGCCCGA		 77 25 52 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0296 GUGCCA---GCUGUGGUCGGGC
CACGGU---CGACACCAGCCCG		 78 20 58 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0297 UGUGCCA---GCUGUGGUCGGG
ACACGGU---CGACACCAGCCC		 30 20 10 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0298 GUGUGCCA---GCUGUGGUCGG
CACACGGU---CGACACCAGCC		 29 10 19 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0299 GGUGUGCCA---GCUGUGGUCG
CCACACGGU---CGACACCAGC		 19 10 9 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0300 UGGUGUGCCA---GCUGUGGUC
ACCACACGGU---CGACACCAG		 23 20 3 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0301 CUGGUGUGCCA---GCUGUGGU
GACCACACGGU---CGACACCA		 45 25 20 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0302 CCUGGUGUGCCA---GCUGUGG
GGACCACACGGU---CGACACC		 70 40 30 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0303 CCCUGGUGUGCCA---GCUGUG
GGGACCACACGGU---CGACAC		 90 32 58 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0304 GCCCUGGUGUGCCA---GCUGU
CGGGACCACACGGU---CGACA		 24 0 24 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0305 AGCCCUGGUGUGCCA---GCUG
UCGGGACCACACGGU---CGAC		 90 NA NA COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0306 GAGCCCUGGUGUGCCA---GCU
CUCGGGACCACACGGU---CGA		 88 NA NA COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0307 GGAGCCCUGGUGUGCCA---GC
CCUCGGGACCACACGGU---CG		 30 18 12 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0308 CCA---GCUGUGGUCGGGCUCC
GGU---CGACACCAGCCCGAGG		 23 42 -19 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0309 GCCA---GCUGUGGUCGGGCUC
CGGU---CGACACCAGCCCGAG		 NA 40 NA COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0310 UGCCA---GCUGUGGUCGGGCU
ACGGU---CGACACCAGCCCGA		 NA 70 NA COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0311 GUGUGCCA---GCUGUGGUCGG
CACACGGU---CGACACCAGCC		 NA 0 NA COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0312 UGGUGUGCCA---GCUGUGGUC
ACCACACGGU---CGACACCAG		 95 38 57 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0313 GGUGUGCCA---GCUGUGGUCG
CCACACGGU---CGACACCAGC		 80 38 42 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0314 UGUGCCA---GCUGUGGUCGGG
ACACGGU---CGACACCAGCCC		 90 34 56 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0315 GCCCUGGUGUGCCA---GCUGU
CGGGACCACACGGU---CGACA		 90 83 7 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0316 GGAAAGCCUGGUAUUCCCA
CCUUUCGGACCAUAAGGGU		 80 28 52 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0317 GAAAGCCUGGUAUUCCCAG
CUUUCGGACCAUAAGGGUC		 58 33 25 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0318 AAAGCCUGGUAUUCCCAGG
UUUCGGACCAUAAGGGUCC		 10 5 5 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0319 AAGCCUGGUAUUCCCAGGC
UUCGGACCAUAAGGGUCCG		 30 21 9 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0320 AGCCUGGUAUUCCCAGGCU
UCGGACCAUAAGGGUCCGA		 82 15 67 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0321 GCCUGGUAUUCCCAGGCUC
CGGACCAUAAGGGUCCGAG		 50 11 39 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0322 CCUGGUAUUCCCAGGCUCC
GGACCAUAAGGGUCCGAGG		 50 20 30 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0323 CUGGUAUUCCCAGGCUCCC
GACCAUAAGGGUCCGAGGG		 32 32 0 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0324 UGGUAUUCCCAGGCUCCCA
ACCAUAAGGGUCCGAGGGU		 40 20 20 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0325 GGUAUUCCCAGGCUCCCAG
CCAUAAGGGUCCGAGGGUC		 20 10 10 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0326 GUAUUCCCAGGCUCCCAGG
CAUAAGGGUCCGAGGGUCC		 23 5 18 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0327 UAUUCCCAGGCUCCCAGGC
AUAAGGGUCCGAGGGUCCG		 88 20 68 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0328 AUUCCCAGGCUCCCAGGCA
UAAGGGUCCGAGGGUCCGU		 30 10 20 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0329 UUCCCAGGCUCCCAGGCAG
AAGGGUCCGAGGGUCCGUC		 30 20 10 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0330 UCCCAGGCUCCCAGGCAGG
AGGGUCCGAGGGUCCGUCC		 24 10 14 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0331 CCCAGGCUCCCAGGCAGGG
GGGUCCGAGGGUCCGUCCC		 92 6 86 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0332 CCAGGCUCCCAGGCAGGGC
GGUCCGAGGGUCCGUCCCG		 50 20 30 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0333 CAGGCUCCCAGGCAGGGCU
GUCCGAGGGUCCGUCCCGA		 75 15 60 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0334 AGGCUCCCAGGCAGGGCUG
UCCGAGGGUCCGUCCCGAC		 90 0 90 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0335 AAAGCCUGGUAUUCCCAGG
UUUCGGACCAUAAGGGUCC		 76 54 22 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0336 AAGCCUGGUAUUCCCAGGC
UUCGGACCAUAAGGGUCCG		 92 40 52 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0337 GGUAUUCCCAGGCUCCCAG
CCAUAAGGGUCCGAGGGUC		 62 3 59 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0338 UAUUCCCAGGCUCCCAGGC
AUAAGGGUCCGAGGGUCCG		 45 5 40 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0339 CCCAGGCUCCCAGGCAGGG
GGGUCCGAGGGUCCGUCCC		 57 67 -10 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0347 AGCAGCAGCGGGACCUAUC
UCGUCGUCGCCCUGGAUAG		 16 0 16 ATXN3 Machado-Joseph disease (MJD)/Spinocerebellar ataxia type 3 (SCA3) c.892_894CAG(8_36) (p.Gln298_Gln305=),c.987G>C rs19392292
18841197
aspsirna0540 UUCAAUAUAAAGGCUGGCG
AAGUUAUAUUUCCGACCGC		 37 8 29 LRRK2 Parkinsons disease (PD) c.4321C>G,p.Arg1441Gly rs33939927
21712955
aspsirna0541 GCUGGCGCUUCUUCUUCCC
CGACCGCGAAGAAGAAGGG		 71 10 61 LRRK2 Parkinsons disease (PD) c.4321C>G,p.Arg1441Gly rs33939927
21712955
aspsirna0542 UAAAGGCUGGCGCUUCUUC
AUUUCCGACCGCGAAGAAG		 20 6 14 LRRK2 Parkinsons disease (PD) c.4321C>G,p.Arg1441Gly rs33939927
21712955
aspsirna0543 UAAAGGCUUGCGCUUCUUC
AUUUCCGAACGCGAAGAAG		 63 75 -12 LRRK2 Parkinsons disease (PD) c.4321C>T,p.Arg1441Cys rs33939927
21712955
aspsirna0544 GCUGACUACAGCAUUGCUC
CGACUGAUGUCGUAACGAG		 40 86 -46 LRRK2 Parkinsons disease (PD) c.6055G>A,p.Gly2019Ser rs34637584
21712955
aspsirna0545 CUACAGCAUUGCUCAGUAC
GAUGUCGUAACGAGUCAUG		 29 4 25 LRRK2 Parkinsons disease (PD) c.6055G>A,p.Gly2019Ser rs34637584
21712955
aspsirna0546 UACAGCAUUGCUCAGUACU
AUGUCGUAACGAGUCAUGA		 46 14 32 LRRK2 Parkinsons disease (PD) c.6055G>A,p.Gly2019Ser rs34637584
21712955
aspsirna0547 AGAUUGCUGACUACAGCAU
UCUAACGACUGAUGUCGUA		 40 7 33 LRRK2 Parkinsons disease (PD) c.6055G>A,p.Gly2019Ser rs34637584
21712955
aspsirna0548 AAGAUUGCUGACUACAGCA
UUCUAACGACUGAUGUCGU		 40 0 40 LRRK2 Parkinsons disease (PD) c.6055G>A,p.Gly2019Ser rs34637584
21712955
aspsirna0876 ACAGAUCAAGACCCUCAAA
UGUCUAGUUCUGGGAGUUU		 36 22 14 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0877 CAGAUCAAGACCCUCAAAA
GUCUAGUUCUGGGAGUUUU		 56 42 14 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0878 AGAUCAAGACCCUCAAAAA
UCUAGUUCUGGGAGUUUUU		 39 20 19 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0879 GAUCAAGACCCUCAAAAAC
CUAGUUCUGGGAGUUUUUG		 56 42 14 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0880 AUCAAGACCCUCAAAAACA
UAGUUCUGGGAGUUUUUGU		 67 39 28 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0881 UCAAGACCCUCAAAAACAA
AGUUCUGGGAGUUUUUGUU		 89 10 79 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0882 CAAGACCCUCAAAAACAAG
GUUCUGGGAGUUUUUGUUC		 30 2 28 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0883 AAGACCCUCAAAAACAAGU
UUCUGGGAGUUUUUGUUCA		 33 0 33 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0884 AGACCCUCAAAAACAAGUU
UCUGGGAGUUUUUGUUCAA		 35 10 25 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0885 GACCCUCAAAAACAAGUUU
CUGGGAGUUUUUGUUCAAA		 59 0 59 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0886 ACCCUCAAAAACAAGUUUG
UGGGAGUUUUUGUUCAAAC		 13 0 13 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0887 CCCUCAAAAACAAGUUUGC
GGGAGUUUUUGUUCAAACG		 35 0 35 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0888 CCUCAAAAACAAGUUUGCC
GGAGUUUUUGUUCAAACGG		 45 9 36 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0889 CUCAAAAACAAGUUUGCCU
GAGUUUUUGUUCAAACGGA		 56 25 31 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0890 UCAAAAACAAGUUUGCCUC
AGUUUUUGUUCAAACGGAG		 45 10 35 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0891 CAAAAACAAGUUUGCCUCC
GUUUUUGUUCAAACGGAGG		 23 20 3 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0892 AAAAACAAGUUUGCCUCCU
UUUUUGUUCAAACGGAGGA		 53 34 19 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0893 AAAACAAGUUUGCCUCCUU
UUUUGUUCAAACGGAGGAA		 47 20 27 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0894 AAACAAGUUUGCCUCCUUC
UUUGUUCAAACGGAGGAAG		 34 9 25 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0928 GCAGCGGGACCUAUCAGGA
CGUCGCCCUGGAUAGUCCU		 52 94 -42 ATXN3 Machado-Joseph Disease (MJD)/Spinocerebellar ataxia type 3 (SCA3) c.209_211CAG(8_36),(p.Gln298_Gln305=) rs19392292
15236410
aspsirna0929 GCAGCAGCGGGACCUAUCA
CGUCGUCGCCCUGGAUAGU		 28 90 -62 ATXN3 Machado-Joseph Disease (MJD)/Spinocerebellar ataxia type 3 (SCA3) c.209_211CAG(8_36),(p.Gln298_Gln305=) rs19392292
15236410
aspsirna0930 GCAGCAGCAGCGGGACCUA
CGUCGUCGUCGCCCUGGAU		 89 50 39 ATXN3 Machado-Joseph Disease (MJD)/Spinocerebellar ataxia type 3 (SCA3) c.209_211CAG(8_36),(p.Gln298_Gln305=) rs19392292
15236410
aspsirna0931 GCAGCAGCAGCAGCGGGAC
CGUCGUCGUCGUCGCCCUG		 80 80 0 ATXN3 Machado-Joseph Disease (MJD)/Spinocerebellar ataxia type 3 (SCA3) c.209_211CAG(8_36),(p.Gln298_Gln305=) rs19392292
15236410
aspsirna1896 AGGGCCUGUGUCACCCUCAGG
UCCCGGACACAGUGGGAGUCC		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1897 GGGCCUGUGUCACCCUCAGGU
CCCGGACACAGUGGGAGUCCA		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1898 GGCCUGUGUCACCCUCAGGUG
CCGGACACAGUGGGAGUCCAC		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1899 GCCUGUGUCACCCUCAGGUGA
CGGACACAGUGGGAGUCCACU		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1900 CCUGUGUCACCCUCAGGUGAG
GGACACAGUGGGAGUCCACUC		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1901 CUGUGUCACCCUCAGGUGAGG
GACACAGUGGGAGUCCACUCC		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1902 UGUGUCACCCUCAGGUGAGGG
ACACAGUGGGAGUCCACUCCC		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1903 GUGUCACCCUCAGGUGAGGGU
CACAGUGGGAGUCCACUCCCA		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1904 UGUCACCCUCAGGUGAGGGUG
ACAGUGGGAGUCCACUCCCAC		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1905 GUCACCCUCAGGUGAGGGUGG
CAGUGGGAGUCCACUCCCACC		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1906 UCACCCUCAGGUGAGGGUGGG
AGUGGGAGUCCACUCCCACCC		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1907 CACCCUCAGGUGAGGGUGGGG
GUGGGAGUCCACUCCCACCCC		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1908 ACCCUCAGGUGAGGGUGGGGA
UGGGAGUCCACUCCCACCCCU		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1909 CCCUCAGGUGAGGGUGGGGAC
GGGAGUCCACUCCCACCCCUG		 78 70 8 Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1910 CCUCAGGUGAGGGUGGGGACC
GGAGUCCACUCCCACCCCUGG		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1911 CUCAGGUGAGGGUGGGGACCG
GAGUCCACUCCCACCCCUGGC		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1912 UCAGGUGAGGGUGGGGACCGA
AGUCCACUCCCACCCCUGGCU		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna3240 CUCGGCUGGCCUCUUGGCU
GAGCCGACCGGAGAACCGA		 10 0 10 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.500delAinsGGCT,p.Tyr167delinsTrpLeu rs59317143
27003758
aspsirna3241 UCGGCUGGCCUCUUGGCUC
AGCCGACCGGAGAACCGAG		 30 10 20 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.500delAinsGGCT,p.Tyr167delinsTrpLeu rs59317143
27003758
aspsirna3242 CGGCUGGCCUCUUGGCUCU
GCCGACCGGAGAACCGAGA		 10 0 10 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.500delAinsGGCT,p.Tyr167delinsTrpLeu rs59317143
27003758
aspsirna3243 GGCUGGCCUCUUGGCUCUU
CCGACCGGAGAACCGAGAA		 20 3 17 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.500delAinsGGCT,p.Tyr167delinsTrpLeu rs59317143
27003758
aspsirna3244 GCUGGCCUCUUGGCUCUUG
CGACCGGAGAACCGAGAAC		 10 0 10 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.500delAinsGGCT,p.Tyr167delinsTrpLeu rs59317143
27003758
aspsirna3245 CUGGCCUCUUGGCUCUUGG
GACCGGAGAACCGAGAACC		 2 10 -8 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.500delAinsGGCT,p.Tyr167delinsTrpLeu rs59317143
27003758
aspsirna3246 UGGCCUCUUGGCUCUUGGA
ACCGGAGAACCGAGAACCU		 40 20 20 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.500delAinsGGCT,p.Tyr167delinsTrpLeu rs59317143
27003758
aspsirna3247 GGCCUCUUGGCUCUUGGAU
CCGGAGAACCGAGAACCUA		 70 5 65 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.500delAinsGGCT,p.Tyr167delinsTrpLeu rs59317143
27003758
aspsirna3248 GCCUCUUGGCUCUUGGAUA
CGGAGAACCGAGAACCUAU		 30 15 15 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.500delAinsGGCT,p.Tyr167delinsTrpLeu rs59317143
27003758
aspsirna3249 CCUCUUGGCUCUUGGAUAA
GGAGAACCGAGAACCUAUU		 42 30 12 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.500delAinsGGCT,p.Tyr167delinsTrpLeu rs59317143
27003758
aspsirna3250 CUCUUGGCUCUUGGAUAAG
GAGAACCGAGAACCUAUUC		 35 22 13 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.500delAinsGGCT,p.Tyr167delinsTrpLeu rs59317143
27003758
aspsirna3251 UCUUGGCUCUUGGAUAAGG
AGAACCGAGAACCUAUUCC		 20 10 10 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.500delAinsGGCT,p.Tyr167delinsTrpLeu rs59317143
27003758
aspsirna3252 CUUGGCUCUUGGAUAAGGU
GAACCGAGAACCUAUUCCA		 11 10 1 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.500delAinsGGCT,p.Tyr167delinsTrpLeu rs59317143
27003758
aspsirna3253 UUGGCUCUUGGAUAAGGUG
AACCGAGAACCUAUUCCAC		 22 13 9 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.500delAinsGGCT,p.Tyr167delinsTrpLeu rs59317143
27003758
aspsirna3254 UGGCUCUUGGAUAAGGUGC
ACCGAGAACCUAUUCCACG		 0 20 -20 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.500delAinsGGCT,p.Tyr167delinsTrpLeu rs59317143
27003758
aspsirna3255 GGCUCUUGGAUAAGGUGCA
CCGAGAACCUAUUCCACGU		 30 24 6 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.500delAinsGGCT,p.Tyr167delinsTrpLeu rs59317143
27003758