| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
| aspsirna1001 | GGAGACUUGCGCAAUGUGA CCUCUGAACGCGUUACACU |
80 | 20 | 60 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | 
|
|
| aspsirna0170 | UGAAGUGAAUCUGGAUGCAG ACUUCACUUAGACCUACGUC |
60 | 10 | 50 | APP | Alzheimers disease | c.2010_2011delGAinsTC (p.Lys670_Met671delinsAsnLeu) | rs28186516 |
|
|
| aspsirna0342 | GACAAAGAUGCUGUGGCCGAU CUGUUUCUACGACACCGGCUA |
74 | 10 | 64 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.281G>C,p.Gly94Ala | rs12191243 |
|
|
| aspsirna0804 | CGAUUCCAUGUUCAUGAGU GCUAAGGUACAAGUACUCA |
80 | 74 | 6 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.281G>C,p.Gly94Ala | rs12191243 |
|
|
| aspsirna0805 | UCGAUUCCAUGUUCAUGAG AGCUAAGGUACAAGUACUC |
50 | 42 | 8 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.281G>C,p.Gly94Ala | rs12191243 |
|
|
| aspsirna1000 | UGGAGACUUGCGCAAUGUG ACCUCUGAACGCGUUACAC |
95 | 10 | 85 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna1002 | GAGACUUGCGCAAUGUGAC CUCUGAACGCGUUACACUG |
96 | 23 | 73 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna1003 | UGGAGACUUGGGCAAUGUG ACCUCUGAACCCGUUACAC |
82 | 5 | 77 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna1004 | GGAGACUUGGGCAAUGUGA CCUCUGAACCCGUUACACU |
20 | 46 | -26 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna1005 | GAGACUUGGGCAAUGUGAC CUCUGAACCCGUUACACUG |
NA | NA | NA | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna3121 | GAUCAAGACCCUCAAAAAC CUAGUUCUGGGAGUUUUUG |
56 | 42 | 14 | KRT6A | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna3122 | CCCUCAAAAACAAGUUUGC GGGAGUUUUUGUUCAAACG |
35 | 0 | 35 | KRT6A | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna3178 | UUGCCAGGUUGCAGCUGCUCUU AACGGUCCAACGUCGACGAGAA |
90 | 26 | 64 | HTT | Huntington disease (HD) | rs362306 | rs362306 |
|
|
| aspsirna3258 | GGCCUCUUGGCUCUUGGAU CCGGAGAACCGAGAACCUA |
80 | 2 | 78 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.500delAinsGGCT,p.Tyr167delinsTrpLeu | rs59317143 |
|
|
| aspsirna3259 | GGCCUCUUGGCUCUUGGAU CCGGAGAACCGAGAACCUA |
73 | 10 | 63 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.500delAinsGGCT,p.Tyr167delinsTrpLeu | rs59317143 |
|