ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0899 | CACACGGAAUGUGAUGGCC GUGUGCCUUACACUACCGG |
NA | NA | NA | HLA-A heavy chain | HLA incompatibility | c.*66A>T | rs1061235 | ||
aspsirna0900 | GAGCUCAGAUAGAAAAGGU CUCGAGUCUAUCUUUUCCA |
20 | NA | NA | HLA-A heavy chain | HLA incompatibility | c.*66A>T | rs1061235 | ||
aspsirna0901 | AAGGAGGGAGCUUCUCUCA UUCCUCCCUCGAAGAGAGU |
30 | NA | NA | HLA-A heavy chain | HLA incompatibility | c.*66A>T | rs1061235 | ||
aspsirna0902 | AGAUACUCCUGCCAUGUGC UCUAUGAGGACGGUACACG |
70 | NA | NA | HLA-A heavy chain | HLA incompatibility | c.*66A>T | rs1061235 | ||
aspsirna0903 | UGAUACACCUGCCAUGUGC ACUAUGUGGACGGUACACG |
60 | NA | NA | HLA-A heavy chain | HLA incompatibility | c.*66A>T | rs1061235 | ||
aspsirna0904 | AAAGUGGAGCAUUCACACU UUUCACCUCGUAAGUGUGA |
90 | NA | NA | B2M | HLA incompatibility | c.31G>C,p.Ala11Pro | rs10489448 | ||
aspsirna0905 | GAUGAGUAUGCCUGCCGUC CUACUCAUACGGACGGCAG |
89 | NA | NA | B2M | HLA incompatibility | c.31G>C,p.Ala11Pro | rs10489448 | ||
aspsirna0906 | UCCAUCCGACAUUGAACUU AGGUAGGCUGUAACUUGAA |
78 | NA | NA | B2M | HLA incompatibility | c.31G>C,p.Ala11Pro | rs10489448 | ||
aspsirna0907 | UUCGAAGCUUGAAGCUAA AAGCUUCGAACUUCGAUU |
89 | NA | NA | B2M | HLA incompatibility | c.31G>C,p.Ala11Pro | rs10489448 | ||
aspsirna0908 | GGUUUACUCACCUCAUCCA CCAAAUGAGUGGAGUAGGU |
70 | NA | NA | B2M | HLA incompatibility | c.31G>C,p.Ala11Pro | rs10489448 | ||
aspsirna0909 | GUGGGAUCGAGACAUCUAA CACCCUAGCUCUGUAGAUU |
82 | NA | NA | B2M | HLA incompatibility | c.31G>C,p.Ala11Pro | rs10489448 | ||
aspsirna0910 | GUGGGAUCGAGACAUCUAA CACCCUAGCUCUGUAGAUU |
40 | NA | NA | B2M | HLA incompatibility | c.31G>C,p.Ala11Pro | rs10489448 | ||
aspsirna0911 | CACACGGAAUGUGAUGGCC GUGUGCCUUACACUACCGG |
NA | NA | NA | HLA-A heavy chain | HLA incompatibility | c.*66A>T | rs1061235 | ||
aspsirna0912 | GAGCUCAGAUAGAAAAGGU CUCGAGUCUAUCUUUUCCA |
30 | NA | NA | HLA-A heavy chain | HLA incompatibility | c.*66A>T | rs1061235 | ||
aspsirna0913 | AAGGAGGGAGCUUCUCUCA UUCCUCCCUCGAAGAGAGU |
35 | NA | NA | HLA-A heavy chain | HLA incompatibility | c.*66A>T | rs1061235 | ||
aspsirna0914 | AGAUACUCCUGCCAUGUGC UCUAUGAGGACGGUACACG |
75 | NA | NA | HLA-A heavy chain | HLA incompatibility | c.*66A>T | rs1061235 | ||
aspsirna0915 | UGAUACACCUGCCAUGUGC ACUAUGUGGACGGUACACG |
80 | NA | NA | HLA-A heavy chain | HLA incompatibility | c.*66A>T | rs1061235 | ||
aspsirna0916 | AAAGUGGAGCAUUCACACU UUUCACCUCGUAAGUGUGA |
89 | NA | NA | B2M | HLA incompatibility | c.31G>C,p.Ala11Pro | rs10489448 | ||
aspsirna0917 | GAUGAGUAUGCCUGCCGUC CUACUCAUACGGACGGCAG |
93 | NA | NA | B2M | HLA incompatibility | c.31G>C,p.Ala11Pro | rs10489448 | ||
aspsirna0918 | UCCAUCCGACAUUGAACUU AGGUAGGCUGUAACUUGAA |
75 | NA | NA | B2M | HLA incompatibility | c.31G>C,p.Ala11Pro | rs10489448 | ||
aspsirna0919 | UUCGAAGCUUGAAGCUAA AAGCUUCGAACUUCGAUU |
88 | NA | NA | B2M | HLA incompatibility | c.31G>C,p.Ala11Pro | rs10489448 | ||
aspsirna0920 | GGUUUACUCACCUCAUCCA CCAAAUGAGUGGAGUAGGU |
70 | NA | NA | B2M | HLA incompatibility | c.31G>C,p.Ala11Pro | rs10489448 | ||
aspsirna0921 | GUGGGAUCGAGACAUCUAA CACCCUAGCUCUGUAGAUU |
80 | NA | NA | B2M | HLA incompatibility | c.31G>C,p.Ala11Pro | rs10489448 | ||
aspsirna0922 | GUGGGAUCGAGACAUCUAA CACCCUAGCUCUGUAGAUU |
45 | NA | NA | B2M | HLA incompatibility | c.31G>C,p.Ala11Pro | rs10489448 |