| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
| aspsirna1012 | CUGAACCCCCUCAAAAGCC GACUUGGGGGAGUUUUCGG |
75 | 64 | 11 | COL1A1 | Osteogenesis Imperfecta (OI) | c.*88T>C | rs1061237 | 
|
|
| aspsirna1013 | CCUCAAAAGCCAAAAAAUG GGAGUUUUCGGUUUUUUAC |
78 | 44 | 34 | COL1A1 | Osteogenesis Imperfecta (OI) | c.*88T>C | rs1061237 |
|
|
| aspsirna1014 | CCCCAAAAGCCAAAAAAU GGGGUUUUCGGUUUUUUA |
80 | 40 | 40 | COL1A1 | Osteogenesis Imperfecta (OI) | c.*88T>C | rs1061237 |
|
|
| aspsirna1015 | CUGAACCCCCUCAAAAGCC GACUUGGGGGAGUUUUCGG |
75 | 64 | 11 | COL1A1 | Osteogenesis Imperfecta (OI) | c.*88T>C | rs1061237 |
|
|
| aspsirna1016 | CCUCAAAAGCCAAAAAAUG GGAGUUUUCGGUUUUUUAC |
78 | 44 | 34 | COL1A1 | Osteogenesis Imperfecta (OI) | c.*88T>C | rs1061237 |
|
|
| aspsirna1017 | CCCCAAAAGCCAAAAAAU GGGGUUUUCGGUUUUUUA |
80 | 40 | 40 | COL1A1 | Osteogenesis Imperfecta (OI) | c.*88T>C | rs1061237 |
|
|
| aspsirna1886 | UCUCCUGGUGAAGCUUGUC AGAGGACCACUUCGAACAG |
40 | 22 | 18 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 |
|
|
| aspsirna1887 | CUCCUGGUGAAGCUUGUCG GAGGACCACUUCGAACAGC |
40 | 25 | 15 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 |
|
|
| aspsirna1888 | UCCUGGUGAAGCUUGUCGU AGGACCACUUCGAACAGCA |
52 | 40 | 12 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 |
|
|
| aspsirna1889 | CCUGGUGAAGCUUGUCGUC GGACCACUUCGAACAGCAG |
47 | 18 | 29 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 |
|
|
| aspsirna1890 | CUGGUGAAGCUUGUCGUCC GACCACUUCGAACAGCAGG |
57 | 2 | 55 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 |
|
|
| aspsirna1891 | UGGUGAAGCUUGUCGUCCC ACCACUUCGAACAGCAGGG |
58 | 10 | 48 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 |
|
|
| aspsirna1892 | CUGGUGAAGCUUGUCGUCC GACCACUUCGAACAGCAGG |
65 | 15 | 50 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 |
|
|
| aspsirna1893 | UGGUGAAGCUUGUCGUCCC ACCACUUCGAACAGCAGGG |
58 | 1 | 57 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 |
|
|
| aspsirna1894 | CUGGUGAAGCUUGUCGUCC GACCACUUCGAACAGCAGG |
60 | 15 | 45 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 |
|
|
| aspsirna1895 | UGGUGAAGCUUGUCGUCCC ACCACUUCGAACAGCAGGG |
60 | 11 | 49 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 |
|
|
| aspsirna3966 | GAACUUUGCUGCUCAGUAU CUUGAAACGACGAGUCAUA |
97 | NA | NA | COL1A1 | NA | NA | NA |
|
|
| aspsirna3967 | GAGCUUUGCUGCUCAGUAU CUUGAAACGACGAGUCAUA |
95 | 97 | 2 | COL1A1 | NA | NA | NA |
|
|
| aspsirna3968 | GACCUUUGCUGCUCAGUAU CUUGAAACGACGAGUCAUA |
95 | 97 | 2 | COL1A1 | NA | NA | NA |
|
|
| aspsirna3969 | GAUCUUUGCUGCUCAGUAU CUUGAAACGACGAGUCAUA |
92 | 97 | 5 | COL1A1 | NA | NA | NA |
|
|
| aspsirna3970 | GAACUUUGCUGCUCAGUAU CUUGAAACGACGAGUCAUA |
95 | NA | NA | COL1A1 | NA | NA | NA |
|
|
| aspsirna3971 | GAACUUUCCUGCUCAGUAU CUUGAAACGACGAGUCAUA |
85 | 95 | 10 | COL1A1 | NA | NA | NA |
|
|
| aspsirna3972 | GAACUUUUCUGCUCAGUAU CUUGAAACGACGAGUCAUA |
90 | 95 | 5 | COL1A1 | NA | NA | NA |
|
|
| aspsirna3973 | GAACUUUACUGCUCAGUAU CUUGAAACGACGAGUCAUA |
92 | 95 | 3 | COL1A1 | NA | NA | NA |
|
|
| aspsirna3974 | GAACUUUGCUGCUCAGUAU CUUGAAACGACGAGUCAUA |
97 | NA | NA | COL1A1 | NA | NA | NA |
|
|
| aspsirna3975 | GAACUUUGCUGCUCACUAU CUUGAAACGACGAGUCAUA |
75 | 97 | 22 | COL1A1 | NA | NA | NA |
|
|
| aspsirna3976 | GAACUUUGCUGCUCAUUAU CUUGAAACGACGAGUCAUA |
85 | 97 | 12 | COL1A1 | NA | NA | NA |
|
|
| aspsirna3977 | GAACUUUGCUGCUCAAUAU CUUGAAACGACGAGUCAUA |
90 | 97 | 7 | COL1A1 | NA | NA | NA |
|
|
| aspsirna3978 | GCAAAUGGCCUCACUGGUG CGUUUACCGGAGUGACCAC |
93 | NA | NA | COL1A1 | NA | NA | NA |
|
|
| aspsirna3979 | GCGAAUGGCCUCACUGGUG CGUUUACCGGAGUGACCAC |
65 | 93 | 28 | COL1A1 | NA | NA | NA |
|
|
| aspsirna3980 | GCCAAUGGCCUCACUGGUG CGUUUACCGGAGUGACCAC |
60 | 93 | 33 | COL1A1 | NA | NA | NA |
|
|
| aspsirna3981 | GCUAAUGGCCUCACUGGUG CGUUUACCGGAGUGACCAC |
70 | 93 | 23 | COL1A1 | NA | NA | NA |
|
|
| aspsirna3982 | GCAAAUGGCCUCACUGGUG CGUUUACCGGAGUGACCAC |
95 | NA | NA | COL1A1 | NA | NA | NA |
|
|
| aspsirna3983 | GCAAAUGCCCUCACUGGUG CGUUUACCGGAGUGACCAC |
45 | 95 | 50 | COL1A1 | NA | NA | NA |
|
|
| aspsirna3984 | GCAAAUGUCCUCACUGGUG CGUUUACCGGAGUGACCAC |
50 | 95 | 45 | COL1A1 | NA | NA | NA |
|
|
| aspsirna3985 | GCAAAUGACCUCACUGGUG CGUUUACCGGAGUGACCAC |
85 | 95 | 10 | COL1A1 | NA | NA | NA |
|
|
| aspsirna3986 | GCAAAUGGCCUCACUGGUG CGUUUACCGGAGUGACCAC |
90 | NA | NA | COL1A1 | NA | NA | NA |
|
|
| aspsirna3987 | GCAAAUGGCCUCACUCGUG CGUUUACCGGAGUGACCAC |
86 | 90 | 4 | COL1A1 | NA | NA | NA |
|
|
| aspsirna3988 | GCAAAUGGCCUCACUUGUG CGUUUACCGGAGUGACCAC |
90 | 90 | 0 | COL1A1 | NA | NA | NA |
|
|
| aspsirna3989 | GCAAAUGGCCUCACUAGUG CGUUUACCGGAGUGACCAC |
90 | 90 | 0 | COL1A1 | NA | NA | NA |
|