| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
| aspsirna0565 | AAUCUGGAUGCAGAAUUCCGA UUAGACCUACGUCUUAAGGCU |
0 | 0 | High discrimination | APP | Alzheimers disease | c.2010_2011delGAinsTC (p.Lys670_Met671delinsAsnLeu) | rs28186516 | 
|
|
| aspsirna0566 | AAGUGAAUCUGGAUGCAGAAU UUCACUUAGACCUACGUCUUA |
0 | 3 | -3 | APP | Alzheimers disease | c.2010_2011delGAinsTC (p.Lys670_Met671delinsAsnLeu) | rs28186516 |
|
|
| aspsirna0567 | UGAAGUGAAUCUGGAUGCA ACUUCACUUAGACCUACGU |
3 | 70 | -67 | APP | Alzheimers disease | c.2010_2011delGAinsTC (p.Lys670_Met671delinsAsnLeu) | rs28186516 |
|
|
| aspsirna0568 | GCGACAGUGAUCAUCAUCACCU CGCUGUCACUAGUAGUAGUGGA |
10 | 60 | -50 | APP | Alzheimers disease | c.2149G>A,p.Val717Ile | rs63750264 |
|
|
| aspsirna0569 | GACAGUGAUCAUCAUCACCUU CUGUCACUAGUAGUAGUGGAA |
64 | 67 | -3 | APP | Alzheimers disease | c.2149G>A,p.Val717Ile | rs63750264 |
|
|
| aspsirna0570 | ACAGUGAUCAUCAUCACCUUG UGUCACUAGUAGUAGUGGAAC |
73 | 68 | 5 | APP | Alzheimers disease | c.2149G>A,p.Val717Ile | rs63750264 |
|
|
| aspsirna0571 | CAGUGAUCAUCAUCACCUUGG GUCACUAGUAGUAGUGGAACC |
38 | 77 | -39 | APP | Alzheimers disease | c.2149G>A,p.Val717Ile | rs63750264 |
|
|
| aspsirna0572 | CGACAGUGAUCAUCAUCACCU GCUGUCACUAGUAGUAGUGGA |
90 | 70 | 20 | APP | Alzheimers disease | c.2149G>A,p.Val717Ile | rs63750264 |
|
|
| aspsirna0573 | CGCGACAGUGAUCAUCAUCACCUUG GCGCUGUCACUAGUAGUAGUGGAAC |
20 | 58 | -38 | APP | Alzheimers disease | c.2149G>A,p.Val717Ile | rs63750264 |
|
|
| aspsirna0574 | GGACAGUCAUCAUCAUCACCUU CCUGUCAGUAGUAGUAGUGGAA |
29 | 75 | -46 | APP | Alzheimers disease | c.2149G>A,p.Val717Ile | rs63750264 |
|
|
| aspsirna0575 | GGACUGUGAUCAUCAUCACCU CCUGACACUAGUAGUAGUGGA |
78 | Moderately effective | Poor discrimination | APP | Alzheimers disease | c.2149G>A,p.Val717Ile | rs63750264 |
|