ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna1914 | CGUCGCUAUCAAGGAA----------CAA GCAGCGAUAGUUCCUU----------GUU |
82 | 10 | 72 | EGFR | Cancer | c.2235_2243delGGAATTAAG, p.Leu747_Glu749del | rs72750426 | ||
aspsirna1915 | GUCGCUAUCAAGGAA----------CAAC CAGCGAUAGUUCCUU----------GUUG |
95 | 0 | 95 | EGFR | Cancer | c.2235_2243delGGAATTAAG, p.Leu747_Glu749del | rs72750426 | ||
aspsirna1916 | UCGCUAUCAAGGAA----------CAAC AGCGAUAGUUCCUU----------GUUG |
90 | 8 | 82 | EGFR | Cancer | c.2235_2243delGGAATTAAG, p.Leu747_Glu749del | rs72750426 | ||
aspsirna1917 | CGCUAUCAAGGAA----------CAACA GCGAUAGUUCCUU----------GUUGU |
95 | 38 | 57 | EGFR | Cancer | c.2235_2243delGGAATTAAG, p.Leu747_Glu749del | rs72750426 | ||
aspsirna1918 | GCUAUCAAGGAA----------CAACAU CGAUAGUUCCUU----------GUUGUA |
80 | 22 | 58 | EGFR | Cancer | c.2235_2243delGGAATTAAG, p.Leu747_Glu749del | rs72750426 | ||
aspsirna1919 | CUAUCAAGGAA----------CAACAUC GAUAGUUCCUU----------GUUGUAG |
93 | 8 | 85 | EGFR | Cancer | c.2235_2243delGGAATTAAG, p.Leu747_Glu749del | rs72750426 | ||
aspsirna1920 | UAUCAAGGAA----------CAACAUCU AUAGUUCCUU----------GUUGUAGA |
82 | 0 | 82 | EGFR | Cancer | c.2235_2243delGGAATTAAG, p.Leu747_Glu749del | rs72750426 | ||
aspsirna1921 | AUCAAGGAA----------CAACAUCUC UAGUUCCUU----------GUUGUAGAG |
70 | 0 | 70 | EGFR | Cancer | c.2235_2243delGGAATTAAG, p.Leu747_Glu749del | rs72750426 | ||
aspsirna1922 | UCAAGGAA----------CAACAUCUCC AGUUCCUU---GUUGUAGAGG |
60 | 5 | 55 | EGFR | Cancer | c.2235_2243delGGAATTAAG, p.Leu747_Glu749del | rs72750426 | ||
aspsirna1923 | CGUCGCUAUCAAGGAA----------CAA GCAGCGAUAGUUCCUU----------GUU |
82 | 10 | 72 | EGFR | Cancer | c.2248G>C,p.A750P | rs12191322 | ||
aspsirna1924 | GUCGCUAUCAAGGAA----------CAAC CAGCGAUAGUUCCUU----------GUUG |
95 | 0 | 95 | EGFR | Cancer | c.2248G>C,p.A750P | rs12191322 | ||
aspsirna1925 | UCGCUAUCAAGGAA----------CAAC AGCGAUAGUUCCUU----------GUUG |
90 | 8 | 82 | EGFR | Cancer | c.2248G>C,p.A750P | rs12191322 | ||
aspsirna1926 | CGCUAUCAAGGAA----------CAACA GCGAUAGUUCCUU----------GUUGU |
95 | 38 | 57 | EGFR | Cancer | c.2248G>C,p.A750P | rs12191322 | ||
aspsirna1927 | GCUAUCAAGGAA----------CAACAU CGAUAGUUCCUU----------GUUGUA |
80 | 22 | 58 | EGFR | Cancer | c.2248G>C,p.A750P | rs12191322 | ||
aspsirna1928 | CUAUCAAGGAA----------CAACAUC GAUAGUUCCUU----------GUUGUAG |
93 | 8 | 85 | EGFR | Cancer | c.2248G>C,p.A750P | rs12191322 | ||
aspsirna1929 | UAUCAAGGAA----------CAACAUCU AUAGUUCCUU----------GUUGUAGA |
82 | 0 | 82 | EGFR | Cancer | c.2248G>C,p.A750P | rs12191322 | ||
aspsirna1930 | AUCAAGGAA----------CAACAUCUC UAGUUCCUU----------GUUGUAGAG |
70 | 0 | 70 | EGFR | Cancer | c.2248G>C,p.A750P | rs12191322 | ||
aspsirna1931 | UCAAGGAA----------CAACAUCUCC AGUUCCUU---GUUGUAGAGG |
60 | 5 | 55 | EGFR | Cancer | c.2248G>C,p.A750P | rs12191322 | ||
aspsirna1932 | UCCCGUCGCUAUCAA---------------AACA AGGGCAGCGAUAGUU---------------UUGU |
95 | 3 | 92 | EGFR | Cancer | c.2235_2249delGGAATTAAGAGAAGC, p.Glu746_Ala750del | rs12191342 | ||
aspsirna1933 | CCGUCGCUAUCAA---------------AACAUC GGCAGCGAUAGUU---------------UUGUAG |
90 | 4 | 86 | EGFR | Cancer | c.2235_2249delGGAATTAAGAGAAGC, p.Glu746_Ala750del | rs12191342 | ||
aspsirna1934 | GUCGCUAUCAA---------------AACAUCUC CAGCGAUAGUU---------------UUGUAGAG |
95 | 10 | 85 | EGFR | Cancer | c.2235_2249delGGAATTAAGAGAAGC, p.Glu746_Ala750del | rs12191342 | ||
aspsirna1935 | CGCUAUCAA---------------AACAUCUCCG GCGAUAGUU---------------UUGUAGAGGC |
70 | 30 | 40 | EGFR | Cancer | c.2235_2249delGGAATTAAGAGAAGC, p.Glu746_Ala750del | rs12191342 | ||
aspsirna1936 | CUAUCAA---------------AACAUCUCCGAA GAUAGUU---------------UUGUAGAGGCUU |
97 | 33 | 64 | EGFR | Cancer | c.2235_2249delGGAATTAAGAGAAGC, p.Glu746_Ala750del | rs12191342 | ||
aspsirna1937 | AUCAA---------------AACAUCUCCGAAAG UAGUU---------------UUGUAGAGGCUUUC |
75 | 5 | 70 | EGFR | Cancer | c.2235_2249delGGAATTAAGAGAAGC, p.Glu746_Ala750del | rs12191342 | ||
aspsirna1938 | CAA---------------AACAUCUCCGAAAGCC GUU---------------UUGUAGAGGCUUUCGG |
70 | 30 | 40 | EGFR | Cancer | c.2235_2249delGGAATTAAGAGAAGC, p.Glu746_Ala750del | rs12191342 | ||
aspsirna1939 | UCCCGUCGCUAUCAA---------------AACA AGGGCAGCGAUAGUU---------------UUGU |
95 | 3 | 92 | EGFR | Cancer | c.2235_2248delGGAATTAAGAGAAGinsAATTC, p.Glu746_Ala750delinsIlePro | rs72750428 | ||
aspsirna1940 | CCGUCGCUAUCAA---------------AACAUC GGCAGCGAUAGUU---------------UUGUAG |
90 | 4 | 86 | EGFR | Cancer | c.2235_2248delGGAATTAAGAGAAGinsAATTC, p.Glu746_Ala750delinsIlePro | rs72750428 | ||
aspsirna1941 | GUCGCUAUCAA---------------AACAUCUC CAGCGAUAGUU---------------UUGUAGAG |
95 | 10 | 85 | EGFR | Cancer | c.2235_2248delGGAATTAAGAGAAGinsAATTC, p.Glu746_Ala750delinsIlePro | rs72750428 | ||
aspsirna1942 | CGCUAUCAA---------------AACAUCUCCG GCGAUAGUU---------------UUGUAGAGGC |
70 | 30 | 40 | EGFR | Cancer | c.2235_2248delGGAATTAAGAGAAGinsAATTC, p.Glu746_Ala750delinsIlePro | rs72750428 | ||
aspsirna1943 | CUAUCAA---------------AACAUCUCCGAA GAUAGUU---------------UUGUAGAGGCUU |
97 | 33 | 64 | EGFR | Cancer | c.2235_2248delGGAATTAAGAGAAGinsAATTC, p.Glu746_Ala750delinsIlePro | rs72750428 | ||
aspsirna1944 | AUCAA---------------AACAUCUCCGAAAG UAGUU---------------UUGUAGAGGCUUUC |
75 | 5 | 70 | EGFR | Cancer | c.2235_2248delGGAATTAAGAGAAGinsAATTC, p.Glu746_Ala750delinsIlePro | rs72750428 | ||
aspsirna1945 | CAA---------------AACAUCUCCGAAAGCC GUU---------------UUGUAGAGGCUUUCGG |
70 | 30 | 40 | EGFR | Cancer | c.2235_2248delGGAATTAAGAGAAGinsAATTC, p.Glu746_Ala750delinsIlePro | rs72750428 |