ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna2137 | CAGCAGCAGCUGCAGCAGA GUCGUCGUCGACGUCGUCU |
95 | 50 | 45 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2138 | AGCAGCAGCUGCAGCAGA UCGUCGUCGACGUCGUCU |
90 | 40 | 50 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2139 | GCAGCAGCUGCAGCAGA CGUCGUCGACGUCGUCU |
85 | 25 | 60 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2140 | CAGCAGCUGCAGCAGA GUCGUCGACGUCGUCU |
90 | 40 | 50 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2141 | AGCAGCUGCAGCAGA UCGUCGACGUCGUCU |
80 | 40 | 40 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2142 | GCAGCUGCAGCAGA CGUCGACGUCGUCU |
70 | 20 | 50 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2143 | CAGCUGCAGCAGA GUCGACGUCGUCU |
60 | 20 | 40 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2144 | CAGCAGCAGCUGCAGCAGA-VP GUCGUCGUCGACGUCGUCU-VP |
56 | 33 | 23 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2145 | AGCAGCAGCUGCAGCAGA-VP UCGUCGUCGACGUCGUCU-VP |
80 | 25 | 55 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2146 | GCAGCAGCUGCAGCAGA-VP CGUCGUCGACGUCGUCU-VP |
70 | 10 | 60 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2147 | CAGCAGCUGCAGCAGA-VP GUCGUCGACGUCGUCU-VP |
80 | 24 | 56 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2148 | CAGCAGCAUCUGCAGCAGU-P GUCGUCGUAGACGUCGUCU-P |
90 | 20 | 70 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2149 | CAGCAGCUGCUGCAGCAGU-P GUCGUCGACGACGUCGUCU-P |
70 | 15 | 55 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2150 | CAGCAGUAGCUGCAGCAGU-P GUCGUCAUCGACGUCGUCU-P |
88 | 18 | 70 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2151 | CAGCAUCAGCUGCAGCAGU-P GUCGUAGUCGACGUCGUCU-P |
89 | 34 | 55 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2152 | CAGCUGCAGCUGCAGCAGU-P GUCGACGUCGACGUCGUCU-P |
45 | 68 | -23 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2153 | CAGUAGCAGCUGCAGCAGU-P GUCAUCGUCGACGUCGUCU-P |
90 | 35 | 55 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2154 | CAUCAGCAGCUGCAGCAGU-VP GUAGUCGUCGACGUCGUCU-VP |
78 | 5 | 73 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2155 | CUGCAGCAGCUGCAGCAGU-P GACGUCGUCGACGUCGUCU-P |
60 | 30 | 30 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2156 | CAGCUGCAGCUGCAGCAGU-VP GUCGACGUCGACGUCGUCU-VP |
40 | 50 | -10 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2157 | CUGCAGCAGCUGCAGCAGU-VP GACGUCGUCGACGUCGUCU-VP |
50 | 45 | 5 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2158 | CAGCUGCAGCUGCAGCAGU-VP GUCGACGUCGACGUCGUCU-VP |
80 | 30 | 50 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2159 | CAGCAGCAGCUGCAGCAGA-P GUCGUCGUCGACGUCGUCU-P |
70 | 27 | 43 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2160 | CAGCAGCAGCUGCAGCAGA-P GUCGUCGUCGACGUCGUCU-P |
30 | 13 | 17 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2161 | AGCAGCAGCUGCAGCAGA-P UCGUCGUCGACGUCGUCU-P |
50 | 30 | 20 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2162 | GCAGCAGCUGCAGCAGA-P CGUCGUCGACGUCGUCU-P |
45 | 10 | 35 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2163 | CAGCAGCUGCAGCAGA-P GUCGUCGACGUCGUCU-P |
49 | 23 | 26 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2164 | UUAGCAGCUGCAGCAGA-P UCGUCGACGUCGUCU-P |
88 | 34 | 54 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2165 | UUGCAGCUGCAGCAGA-P CGUCGACGUCGUCU-P |
67 | 22 | 45 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2166 | UUCAGCUGCAGCAGA-P GUCGACGUCGUCU-P |
78 | 21 | 57 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2167 | CAGUUCAGCUGCAGCAGAU-P GUCAAGUCGACGUCGUCUU-P |
59 | 11 | 48 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2168 | CAGCAGUUCAGCUGCAGCAGU-P GUCGUCAAGUCGACGUCGUCU-P |
89 | 12 | 77 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |