ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0932 | CUGCUGACAAAGAUGCUGU GACGACUGUUUCUACGACA |
85 | 90 | -5 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.281G>C (p.Gly94Ala) | rs12191243 | ![]() |
|
aspsirna0933 | CAAAGAUGCUGUGGCCGAU GUUUCUACGACACCGGCUA |
78 | 65 | 13 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.281G>C (p.Gly94Ala) | rs12191243 | ![]() |
|
aspsirna0934 | CAAAGAUGCUGUGGCCGAU GUUUCUACGACACCGGCUA |
80 | 34 | 46 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.281G>C (p.Gly94Ala) | rs12191243 | ![]() |
|
aspsirna0936 | GACAAAGAUGCUGUGGCCGAU CUGUUUCUACGACACCGGCUA |
87 | 20 | 67 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.281G>C (p.Gly94Ala) | rs12191243 | ![]() |
|
aspsirna3567 | GACAAAGAUGCUGUGGCCGAU CUGUUUCUACGACACCGGCUA |
87 | 20 | 67 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.281G>C (p.Gly94Ala) | rs12191243 | ![]() |
|
aspsirna3568 | GACAAAGAUGCUGUGGCCGAU CUGUUUCUACGACACCGGCUA |
87 | 20 | 67 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.281G>C (p.Gly94Ala) | rs12191243 | ![]() |