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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 1 * 1 are 7
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM2617	TGUACGCGGAAUACUUCGAUU UCGAAGUAUUCCGCGUACGUU	Mutation* 5-O-Methyl 0	1 * 1 0	Base; Sugar 0	70 percent target mRNA inhibition	18094121
SM2619	TUAGUCGAAUGCAAGACAAUT UUGUCUUGCAUUCGACUAAUT	Mutation* 5-O-Methyl 0	1 * 1 0	Base; Sugar 0	54 percent target mRNA inhibition	18094121
SM2621	TUAGUCGAAUGCAAGACAAUT TUGUCUUGCAUUCGACUAAUT	Mutation* 5-O-Methyl Mutation* 5-O-Methyl	1 * 1 1 * 1	Base; Sugar Base; Sugar	61 percent target mRNA inhibition	18094121
SM2623	TUAAGAUCUGUUAUCCGCAUT UGCGGAUAACAGAUCUUAAUT	Mutation* 5-O-Methyl 0	1 * 1 0	Base; Sugar 0	83 percent target mRNA inhibition	18094121
SM2625	TUAAGAUCUGUUAUCCGCAUT TGCGGAUAACAGAUCUUAAUT	Mutation* 5-O-Methyl Mutation* 5-O-Methyl	1 * 1 1 * 1	Base; Sugar Base; Sugar	68 percent target mRNA inhibition	18094121
SM2632	TUAAGAUCUGUUAUCCGCAUT UGCGGAUAACAGAUCUUAAUT	Mutation* 5-O-Methyl 0	1 * 1 0	Base; Sugar 0	4 percent target mRNA inhibition	18094121
SM2634	TUAAGAUCUGUUAUCCGCAUT TGCGGAUAACAGAUCUUAAUT	Mutation* 5-O-Methyl Mutation* 5-O-Methyl	1 * 1 1 * 1	Base; Sugar Base; Sugar	0 percent target mRNA inhibition	18094121