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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 11 are 16
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM2779	CUUACGCUGAGUACUUCGATT TCGAAGUACUCAGCGUAAGTT	2,4-Difluorotoluene-2-Deoxyribonucleotide 0	11 0	Base 0	NA	20610434
SM2783	CUUACGCUGAGUACUUCGATT TCGAAGUACUCAGCGUAAGTT	2,4-Difluorotoluene 0	11 0	Base 0	NA	20610434
SM2787	CUUACGCUGAGUACUUCGATT TCGAAGUACUCAGCGUAAGTT	5-Nitroindole-2-Deoxyribonucleotide 0	11 0	Base 0	NA	20610434
SM2791	CUUACGCUGAGUACUUCGATT TCGAAGUACUCAGCGUAAGTT	5-Nitroindole-2-Deoxyribonucleotide 0	11 0	Base 0	NA	20610434
SM2795	CUUACGCUGAGUACUUCGATT TCGAAGUACUCAGCGUAAGTT	2-Deoxynebularine 0	11 0	Base 0	NA	20610434
SM2799	CUUACGCUGAGUACUUCGATT TCGAAGUACUCAGCGUAAGTT	Nebularine 0	11 0	Base 0	NA	20610434
SM2803	CUUACGCUGAGUACUUCGATT TCGAAGUACUCAGCGUAAGTT	2-Deoxy-2-Aminopurine-2-Deoxyribonucleotide 0	11 0	Base 0	NA	20610434
SM2807	CUUACGCUGAGUACUUCGATT TCGAAGUACUCAGCGUAAGTT	2-Aminopurineribonucleotide 0	11 0	Base 0	NA	20610434
SM2811	CUUACGCUGAGUACUUCGATT TCGAAGUACUCAGCGUAAGTT	2-Deoxyinosine 0	11 0	Base 0	NA	20610434
SM2815	CUUACGCUGAGUACUUCGATT TCGAAGUACUCAGCGUAAGTT	Inosine 0	11 0	Base 0	NA	20610434
SM2819	UUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAATT	Abasic(2-hydroxymethyl-tetrahydrofuran-3-ol) 0	11 0	Base 0	NA	20610434
SM2846	AAGUAAGGACCAGAGACAATT UUGUCUCUGGUCCUUACUUTT	2,4-difluorotoluene ribonucleotide 0	11 0	Base 0	IC-50 = 0.039 nM for target mRNA	20610434
SM3770	ACGGCUCGCUACCCUCGACTT GUCGAGGGUAGCGAGCCGUTT	2-Deoxy-2-Fluoro 0	11 0	Sugar 0	83 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3814	AUGGGAGAAGUAGUCCCCCTT GGGGGACUACUUCUCCCAUTT	2-O-Methyl 2-O-Methyl	11 8	Sugar Sugar	84 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM4138	AGAAACGCAGUAAUCCGGATT UCCGGAUUACUGCGUUUCUTT	2-O-Methyl 2-O-Methyl	11 11	Sugar Sugar	82 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM4146	CUCCGACAGAUGAAGGAAATT UUUCCUUCAUCUGUCGGAGTT	2-O-Methyl 2-O-Methyl	11 12	Sugar Sugar	72 percent target mRNA inhibition	US20120088815A1, EP2415869A1