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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 11,14 are 3
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM3686	GGAGCACGCUUACUACCUUTT AAGGUAGUAAGCGUGCUCCTT	2-O-Methyl 2-O-Methyl	11,14 5,8	Sugar Sugar	69 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM4073	AAAGGGGAGUUGCUGGAAGTT CUUCCAGCAACUCCCCUUUTT	2-O-Methyl 2-O-Methyl	11,14 5,8	Sugar Sugar	74 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM4074	AAAGGGGAGUUGCUGGAAGTT CUUCCAGCAACUCCCCUUUTT	2-O-Methyl 2-O-Methyl	11,14 5	Sugar Sugar	76 percent target mRNA inhibition	US20120088815A1, EP2415869A1