Browse By

Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 14,15 are 2
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM3468	AACCCACCACAGCUAGAACUU AAGUUCUAGCUGUGGUGGGUU	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	14,15 7,8	Sugar Sugar	57 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3475	AACCCACCACAGCUAGAACUU AAGUUCUAGCUGUGGUGGGUU	2-O-Methyl 0	14,15 0	Sugar 0	79 percent target mRNA inhibition	US20120088815A1, EP2415869A1