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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

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• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 15 are 7
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM2470	CUGGGAUGCCUUUTT AAAGGCAUCCCAGCCUCCGTT	Assymetric siRNA (3-End Overhang) Assymetric siRNA (3-End Overhang)	15 1	NA NA	14 percent target mRNA inhibition	23135004
SM2656	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	Morpholinouridine 0	15 0	Sugar 0	88 percent target mRNA inhibition	19233658
SM3279	GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT	Altritol nucleic acid 0	15 0	Sugar 0	44 percent target mRNA inhibition	17264131
SM3530	GCGAGCAGAGAAUCUACCUTT AGGUAGAUUCUCUGCUCGCTT	2-O-Methyl 2-O-Methyl	15 4	Sugar Sugar	90 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3605	ACCGACGAUUCUUCUACUCTT GAGUAGAAGAAUCGUCGGUTT	2-O-Methyl 2-O-Methyl	15 4,10,11	Sugar Sugar	67 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3690	GGCGGGCUCUUUCCUAUUCTT GAAUAGGAAAGAGCCCGCCTT	2-O-Methyl 2-O-Methyl	15 4	Sugar Sugar	69 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3746	CGCCCCCCUCAAGCUACCGTT CGGUAGCUUGAGGGGGGCGTT	2-O-Methyl 2-O-Methyl	15 4	Sugar Sugar	76 percent target mRNA inhibition	US20120088815A1, EP2415869A1