Browse By

Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 15,20 are 6
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM4555	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	Triazole-linked nucleic acid 2-Deoxythymidine	15,20 20,21	Backbone Sugar	86 percent target mRNA inhibition	22260772
SM4556	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	Triazole-linked nucleic acid Triazole-linked nucleic acid	15,20 20	Backbone Backbone	43 percent target mRNA inhibition	22260772
SM4570	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	Triazole-linked nucleic acid 2-Deoxythymidine	15,20 20,21	Backbone Sugar	98 percent target mRNA inhibition	22260772
SM4571	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	Triazole-linked nucleic acid Triazole-linked nucleic acid	15,20 20	Backbone Backbone	81 percent target mRNA inhibition	22260772
SM4585	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	Triazole-linked nucleic acid 2-Deoxythymidine	15,20 20,21	Backbone Sugar	97 percent target mRNA inhibition	22260772
SM4586	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	Triazole-linked nucleic acid Triazole-linked nucleic acid	15,20 20	Backbone Backbone	85 percent target mRNA inhibition	22260772