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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 17,21 are 4
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM2701	UUCUCCGAACGUGUCACGUUUU ACGUGACACGUUCGGAGAAUUU	UnLocked nucleic acid Unlocked nucleic acid* Locked nucleic acid	17,21 6 * 20,21	Sugar Sugar	2.87 (log-10 CVB-3 titre pfu/ml)	20005874
SM2702	UUCUCCGAACGUGUCACGUUUU ACGUGACACGUUCGGAGAAUUU	UnLocked nucleic acid Unlocked nucleic acid* Locked nucleic acid	17,21 7 * 20,21	Sugar Sugar	2.9 (log-10 CVB-3 titre pfu/ml)	20005874
SM2703	UUCUCCGAACGUGUCACGUUUU ACGUGACACGUUCGGAGAAUUU	UnLocked nucleic acid Locked nucleic acid	17,21 20,21	Sugar Sugar	2.55 (log-10 CVB-3 titre pfu/ml)	20005874
SM2704	UUCUCCGAACGUGUCACGUUUU ACGUGACACGUUCGGAGAAUUU	UnLocked nucleic acid 0	17,21 0	Sugar 0	2.56 (log-10 CVB-3 titre pfu/ml)	20005874