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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 19* 20,21 are 3
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM2333	CUGGUAAAGCAUUCAGUATT AUACUGAAUGCUUUACCAGTT	Aminoisonucleotide-thymidine* 2-Deoxythymidine 2-Deoxythymidine	19* 20,21 20,21	Base Sugar	85 percent target mRNA inhibition	17539595
SM2398	GCAACUCAUGGUUCAUGCUTT AGCAUGAACCAUGAGUUGCTT	D-Isonucleoside-uracil* 2-Deoxythymidine 2-Deoxythymidine	19* 20,21 20,21	Base Sugar	0 percent target mRNA inhibition	23682837
SM2399	GCAACUCAUGGUUCAUGCUTT AGCAUGAACCAUGAGUUGCTT	L-Isonucleoside uracil* 2-Deoxythymidine 2-Deoxythymidine	19* 20,21 20,21	Base Sugar	0 percent target mRNA inhibition	23682837