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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 2,12 are 3
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM3561	CUAGAGGAUCUUGAAGACCTT GGUCUUCAAGAUCCUCUAGTT	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	2,12 7,17	Sugar Sugar	67 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3949	UUACCCCGAUUCAGCCUCUTT AGAGGCUGAAUCGGGGUAATT	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	2,12 7,17	Sugar Sugar	82 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM4033	CUAGAGGAUCUUGAAGACCTT GGUCUUCAAGAUCCUCUAGTT	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	2,12 7,17	Sugar Sugar	91 percent target mRNA inhibition	US20120088815A1, EP2415869A1