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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 24,25 * 25 are 3
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM4535	GGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG	2-Deoxyribonucleotide* 1-Aminohexane 0	24,25 * 25 0	Sugar; Phosphate 0	79 percent target mRNA inhibition	22236254
SM4537	GGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG	2-Deoxyribonucleotide* 1-Aminohexane 1-Aminohexane	24,25 * 25 27	Sugar; Phosphate Phosphate	45 percent target mRNA inhibition	22236254
SM4539	GGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG	2-Deoxyribonucleotide* 1-Aminohexane 1-Aminohexane	24,25 * 25 1	Sugar; Phosphate Phosphate	45 percent target mRNA inhibition	22236254