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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
- By modification in sense strand
- By modification position in sense strand
- By modification in antisense strand
- By modification position in antisense strand
- Reference
Total number of Results for 3,7 are 4
Results from 0 - 25
| SMDBid | siRNA (sense/antisense) 5'>3' | Modification (sense/antisense) | Position (sense/antisense) |
Modified component (sense/antisense) |
Efficacy (%) | Reference |
|---|
| SM3277 |
GUAUUGACAGCUAUUCGAATT
UUCGAAUAGCUGUCAAUACTT |
Altritol nucleic acid
0 |
3,7
0 |
Sugar
0 |
NA | 17264131 |
| SM3549 |
AAUAAGCAGCUCGCGCUCCTT
GGAGCGCGAGCUGCUUAUUTT |
2-O-Methyl
2-O-Methyl |
3,7
12,15 |
Sugar
Sugar |
68 percent target mRNA inhibition | US20120088815A1, EP2415869A1 |
| SM4030 |
AAUAAGCAGCUCGCGCUCCTT
GGAGCGCGAGCUGCUUAUUTT |
2-O-Methyl
2-O-Methyl |
3,7
16 |
Sugar
Sugar |
54 percent target mRNA inhibition | US20120088815A1, EP2415869A1 |
| SM4045 |
UUUGAUCAGCGGAGACUCGTT
CGAGUCUCCGCUGAUCAAATT |
2-O-Methyl
2-O-Methyl |
3,7
12,16 |
Sugar
Sugar |
89 percent target mRNA inhibition | US20120088815A1, EP2415869A1 |