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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
- By modification in sense strand
- By modification position in sense strand
- By modification in antisense strand
- By modification position in antisense strand
- Reference
Total number of Results for 3,9 are 3
Results from 0 - 25
| SMDBid | siRNA (sense/antisense) 5'>3' | Modification (sense/antisense) | Position (sense/antisense) |
Modified component (sense/antisense) |
Efficacy (%) | Reference |
|---|
| SM3585 |
GAUACUUCUGGUUCCCUCCTT
GGAGGGAACCAGAAGUAUCTT |
2-O-Methyl
2-O-Methyl |
3,9
10,16 |
Sugar
Sugar |
45 percent target mRNA inhibition | US20120088815A1, EP2415869A1 |
| SM3821 |
GGUAGGGUUGAAGAGACUUTT
AAGUCUCUUCAACCCUACCTT |
2-O-Methyl
2-O-Methyl |
3,9
10,16 |
Sugar
Sugar |
94 percent target mRNA inhibition | US20120088815A1, EP2415869A1 |
| SM3945 |
AACAGCCUUACCCCGAUUCTT
GAAUCGGGGUAAGGCUGUUTT |
2-O-Methyl
2-O-Methyl |
3,9
10,16 |
Sugar
Sugar |
68 percent target mRNA inhibition | US20120088815A1, EP2415869A1 |