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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 4 are 7
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM3658	GAAUAACCUGAACGUCACCTT GGUGACGUUCAGGUUAUUCTT	2-O-Methyl 2-O-Methyl	4 15	Sugar Sugar	55 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3710	UCCUAGCUGUCUUGUCCCUTT AGGGACAAGACAGCUAGGATT	2-O-Methyl 2-O-Methyl	4 15	Sugar Sugar	71 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3722	GAGUAUUUCCGCUGGAACUTT AGUUCCAGCGGAAAUACUCTT	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	4 15	Sugar Sugar	75 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3738	GUCUAUGCCAAGAAGGGAGTT CUCCCUUCUUGGCAUAGACTT	2-O-Methyl 2-O-Methyl	4 15	Sugar Sugar	76 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3914	UUCUAACCGGGCAGCUUCUTT AGAAGCUGCCCGGUUAGAATT	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	4 15	Sugar Sugar	72 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3986	AUCUACCCAGCUCUCCCUUTT AAGGGAGAGCUGGGUAGAUTT	2-O-Methyl 2-O-Methyl	4 15	Sugar Sugar	77 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM4050	AGUUAACCCGGGACUUGGATT UCCAAGUCCCGGGUUAACUTT	2-O-Methyl 2-O-Methyl	4 3	Sugar Sugar	91 percent target mRNA inhibition	US20120088815A1, EP2415869A1