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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


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• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 4,13 are 3
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM3348	AGACGAGCUGAGCGAGAAGTT TTUCUGCUCGACUCGCUCUUC	Locked nucleic acid Locked nucleic acid	4,13 4,18	Sugar Sugar	NA	12834349
SM3578	AGCCACAUUUCUAGGAGAUTT AUCUCCUAGAAAUGUGGCUTT	2-O-Methyl 2-O-Methyl	4,13 13	Sugar Sugar	29 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3721	GAGUAUUUCCGCUGGAACUTT AGUUCCAGCGGAAAUACUCTT	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	4,13 6,15	Sugar Sugar	73 percent target mRNA inhibition	US20120088815A1, EP2415869A1