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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 8 are 18
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM2654	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	Morpholinouridine 0	8 0	Sugar 0	84 percent target mRNA inhibition	19233658
SM3452	AGCGCUUAAAGGGCGAGAAGAUU UCUUCUCGCCCUUUAAGCGCUUU	2-O-Methyl 2-O-Methyl	8 14,15	Sugar Sugar	41 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3453	AGCGCUUAAAGGGCGAGAAGAUU UCUUCUCGCCCUUUAAGCGCUUU	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	8 14	Sugar Sugar	47 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3454	AGCGCUUAAAGGGCGAGAAGAUU UCUUCUCGCCCUUUAAGCGCUUU	2-O-Methyl 2-O-Methyl	8 15	Sugar Sugar	83 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3457	AGCGCUUAAAGGGCGAGAAGAUU UCUUCUCGCCCUUUAAGCGCUUU	2-O-Methyl 0	8 0	Sugar 0	85 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3462	AGCGCUUAAAGGGCGGAAGAUU UCUUCUCGCCCUUUAAGCGCUUU	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	8 15	Sugar Sugar	79 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3522	CCCCAGGUAACGAUUUUCUTT AGAAAAUCGUUACCUGGGGTT	2-O-Methyl 2-O-Methyl	8 11	Sugar Sugar	70 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3598	GAAGAGUUAACCCGGGACUTT AGUCCCGGGUUAACUCUUCTT	2-O-Methyl 2-O-Methyl	8 11	Sugar Sugar	51 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3634	AAACCCCUAGAGGGCAAGUTT ACUUGCCCUCUAGGGGUUUTT	2-O-Methyl 2-O-Methyl	8 11	Sugar Sugar	75 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3650	AGCGGGGUAUGAAGAGCUUTT AAGCUCUUCAUACCCCGCUTT	2-O-Methyl 2-O-Methyl	8 11	Sugar Sugar	82 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3698	CUCUCCUACCUUCUCCUCUTT AGAGGAGAAGGUAGGAGAGTT	2-Deoxy-2-Fluoro 0	8 0	Sugar 0	78 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3838	AAGGACCUAGAGGAGUCACTT GUGACUCCUCUAGGUCCUUTT	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	8 11	Sugar Sugar	88 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3978	GCUGAACUAGUCGAAAGAATT UUCUUUCGACUAGUUCAGCTT	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	8 11	Sugar Sugar	79 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM4062	GGAACCUCACAUCAACGCGCATT UGCGCGUUGAUGUGAGGUUCCTT	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	8 2,8,11	Sugar Sugar	65 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM4066	UGAACGUCACCGAGGAGAATT UUCUCCUCGGUGACGUUCATT	2-O-Methyl 2-O-Methyl	8 18	Sugar Sugar	85 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM4094	AAACCUCAGCCCUAACGGUTT ACCGUUAGGGCUGAGGUUUTT	2-O-Methyl 2-O-Methyl	8 6	Sugar Sugar	70 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM4150	AAGGACCUAGAGGAGUCACTT GUGACUCCUCUAGGUCCUUTT	2-O-Methyl 2-O-Methyl	8 2	Sugar Sugar	80 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM4214	AGAGAGGUGGAGGUAUCUCTT GAGAUACCUCCACCUCUCUTT	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	8 5	Sugar Sugar	88 percent target mRNA inhibition	US20120088815A1, EP2415869A1