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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
  • By modification in sense strand

  • By modification position in sense strand

  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for 17511001 are 32
    Results from 25 - 50
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM2573
    UGGCCAAUGCCAAGGAGAUUU
    AUCUCCUUGGCAUUGGCCAUU
    2-Deoxy-2-Fluoro
    0
    1,4,5,8,10,11,19,20,21
    0
    Sugar
    0
    87 percent target mRNA inhibition
    17511001
    SM2574
    UGGCCAAUGCCAAGGAGAUUU
    AUCUCCUUGGCAUUGGCCAUU
    0
    2-Deoxy-2-Fluoro
    0
    1,9,10,12,15,16,19
    0
    Sugar
    81 percent target mRNA inhibition
    17511001
    SM2575
    UGGCCAAUGCCAAGGAGAUUU
    AUCUCCUUGGCAUUGGCCAUU
    0
    2-Deoxy-2-Fluoro
    0
    2,3,4,5,6,7,8,11,13,14,17,18,20,21
    0
    Sugar
    87 percent target mRNA inhibition
    17511001
    SM2576
    UGGCCAAUGCCAAGGAGAUUU
    AUCUCCUUGGCAUUGGCCAUU
    2-Deoxy-2-Fluoro
    2-Deoxy-2-Fluoro
    2,3,6,7,9,12,13,14,15,16,17,18
    1,9,10,12,15,16,19
    Sugar
    Sugar
    62 percent target mRNA inhibition
    17511001
    SM2577
    UGGCCAAUGCCAAGGAGAUUU
    AUCUCCUUGGCAUUGGCCAUU
    2-Deoxy-2-Fluoro
    2-Deoxy-2-Fluoro
    1,4,5,8,10,11,19,20,21
    2,3,4,5,6,7,8,11,13,14,17,18,20,21
    Sugar
    Sugar
    71 percent target mRNA inhibition
    17511001
    SM2578
    UGGCCAAUGCCAAGGAGAUUU
    AUCUCCUUGGCAUUGGCCAUU
    2-Deoxy-2-Fluoro
    2-Deoxy-2-Fluoro
    1,4,5,8,10,11,19,20,21
    1,9,10,12,15,16,19
    Sugar
    Sugar
    83 percent target mRNA inhibition
    17511001
    SM2579
    UGGCCAAUGCCAAGGAGAUUU
    AUCUCCUUGGCAUUGGCCAUU
    2-Deoxy-2-Fluoro
    2-Deoxy-2-Fluoro
    2,3,6,7,9,12,13,14,15,16,17,18
    2,3,4,5,6,7,8,11,13,14,17,18,20,21
    Sugar
    Sugar
    69 percent target mRNA inhibition
    17511001