Browse By

Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
  • By modification in sense strand

  • By modification position in sense strand

  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for 25233814 are 64
    Results from 25 - 50
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM4258
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    22,23
    1,2
    Sugar
    Sugar
    98 percent target mRNA inhibition
    25233814
    SM4259
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,22,23
    0
    Sugar
    0
    0 percent target mRNA inhibition
    25233814
    SM4260
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    1,2,22,23
    22,23
    Sugar
    Sugar
    0 percent target mRNA inhibition
    25233814
    SM4261
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    1,2,22,23
    1,2
    Sugar
    Sugar
    20 percent target mRNA inhibition
    25233814
    SM4262
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    0
    Serinol nucleic acid
    0
    1,2,22,23
    0
    Sugar
    96 percent target mRNA inhibition
    25233814
    SM4263
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    1,2
    1,2,22,23
    Sugar
    Sugar
    90 percent target mRNA inhibition
    25233814
    SM4264
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    22,23
    1,2,22,23
    Sugar
    Sugar
    99 percent target mRNA inhibition
    25233814
    SM4265
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    1,2,22,23
    1,2,22,23
    Sugar
    Sugar
    25 percent target mRNA inhibition
    25233814
    SM4266
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23
    0
    Sugar
    0
    0 percent target mRNA inhibition
    25233814
    SM4267
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    2-O-Methyl ribose
    0
    1,2,22,23
    0
    Sugar
    0
    56 percent target mRNA inhibition
    25233814
    SM4268
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    0
    2-O-Methyl ribose
    0
    1,2,22,23
    0
    Sugar
    98 percent target mRNA inhibition
    25233814
    SM4269
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,23
    0
    Sugar
    0
    93 percent target mRNA inhibition
    25233814
    SM4270
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,22,23
    0
    Sugar
    0
    96 percent target mRNA inhibition
    25233814
    SM4271
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,3,21,22,23
    0
    Sugar
    0
    96 percent target mRNA inhibition
    25233814
    SM4272
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,3,4,5,19,20,21,22,23
    0
    Sugar
    0
    90 percent target mRNA inhibition
    25233814
    SM4273
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,3,4,5,6,7,17,18,19,20,21,22,23
    0
    Sugar
    0
    78 percent target mRNA inhibition
    25233814
    SM4274
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    1,23
    23
    Sugar
    Sugar
    96 percent target mRNA inhibition
    25233814
    SM4275
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    1,2,22,23
    22,23
    Sugar
    Sugar
    94 percent target mRNA inhibition
    25233814
    SM4276
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    1,2,3,21,22,23
    21,22,23
    Sugar
    Sugar
    88 percent target mRNA inhibition
    25233814
    SM4277
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    1,2,3,4,5,19,20,21,22,23
    19,20,21,22,23
    Sugar
    Sugar
    50 percent target mRNA inhibition
    25233814
    SM4278
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    1,2,3,4,5,6,7,17,18,19,20,21,22,23
    17,18,19,20,21,22,23
    Sugar
    Sugar
    20 percent target mRNA inhibition
    25233814
    SM4279
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,23
    0
    Sugar
    0
    10 percent target mRNA inhibition
    25233814
    SM4280
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,22,23
    0
    Sugar
    0
    0 percent target mRNA inhibition
    25233814
    SM4281
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,3,21,22,23
    0
    Sugar
    0
    35 percent target mRNA inhibition
    25233814
    SM4282
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,3,4,5,19,20,21,22,23
    0
    Sugar
    0
    0 percent target mRNA inhibition
    25233814