Browse By

Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
  • By modification in sense strand

  • By modification position in sense strand

  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for 0 are 558
    Results from 425 - 450
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM4106
    CCAGCGAGCCCAAAAGAAATT
    UUUCUUUUGGGCUCGCUGGTT
    2-Deoxy-2-Fluoro
    0
    2,11
    0
    Sugar
    0
    85 percent target mRNA inhibition
    US20120088815A1, EP2415869A1
    SM4186
    AUCCUGCAGAAGAAGCCUCTT
    GAGGCUUCUUCUGCAGGAUTT
    2-O-Methyl
    0
    5,7
    0
    Sugar
    0
    74 percent target mRNA inhibition
    US20120088815A1, EP2415869A1
    SM4232
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2
    0
    Sugar
    0
    93 percent target mRNA inhibition
    25233814
    SM4233
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    22,23
    0
    Sugar
    0
    90 percent target mRNA inhibition
    25233814
    SM4240
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,22,23
    0
    Sugar
    0
    98 percent target mRNA inhibition
    25233814
    SM4247
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23
    0
    Sugar
    0
    0 percent target mRNA inhibition
    25233814
    SM4248
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    2-O-Methyl ribose
    0
    1,2,22,23
    0
    Sugar
    0
    96 percent target mRNA inhibition
    25233814
    SM4251
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2
    0
    Sugar
    0
    96 percent target mRNA inhibition
    25233814
    SM4252
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    22,23
    0
    Sugar
    0
    91 percent target mRNA inhibition
    25233814
    SM4259
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,22,23
    0
    Sugar
    0
    0 percent target mRNA inhibition
    25233814
    SM4266
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23
    0
    Sugar
    0
    0 percent target mRNA inhibition
    25233814
    SM4267
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    2-O-Methyl ribose
    0
    1,2,22,23
    0
    Sugar
    0
    56 percent target mRNA inhibition
    25233814
    SM4269
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,23
    0
    Sugar
    0
    93 percent target mRNA inhibition
    25233814
    SM4270
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,22,23
    0
    Sugar
    0
    96 percent target mRNA inhibition
    25233814
    SM4271
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,3,21,22,23
    0
    Sugar
    0
    96 percent target mRNA inhibition
    25233814
    SM4272
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,3,4,5,19,20,21,22,23
    0
    Sugar
    0
    90 percent target mRNA inhibition
    25233814
    SM4273
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,3,4,5,6,7,17,18,19,20,21,22,23
    0
    Sugar
    0
    78 percent target mRNA inhibition
    25233814
    SM4279
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,23
    0
    Sugar
    0
    10 percent target mRNA inhibition
    25233814
    SM4280
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,22,23
    0
    Sugar
    0
    0 percent target mRNA inhibition
    25233814
    SM4281
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,3,21,22,23
    0
    Sugar
    0
    35 percent target mRNA inhibition
    25233814
    SM4282
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,3,4,5,19,20,21,22,23
    0
    Sugar
    0
    0 percent target mRNA inhibition
    25233814
    SM4283
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,3,4,5,6,7,17,18,19,20,21,22,23
    0
    Sugar
    0
    0 percent target mRNA inhibition
    25233814
    SM4289
    AACCUUACCCACCUCAUGUAUCU
    AUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,22,23
    0
    Sugar
    0
    78 percent target mRNA inhibition
    25233814
    SM4293
    AACCUUACCCACCUCAUGUAUCU
    AUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,22,23
    0
    Sugar
    0
    5 percent target mRNA inhibition
    25233814
    SM4355
    AAGUAAGGACCAGAGACAAA
    UUUGUCUCUGGUCCUUACUU
    2-O-(2-methoxyethyl)ribose
    0
    1,2,3
    0
    Sugar
    0
    67 percent target mRNA inhibition
    15974578