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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
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  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for Deoxyadenine* Mismatch are 3
    Results from 0 - 25
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM2433
    GGAUACUGCCAAUCUCUAGGUUUUU
    CCUAGAGAUUGGCAGUAUCCAAAAA
    Deoxyadenine* Mismatch
    Deoxyadenine* Mismatch
    21,22,23,24,25 * 6,9,12,16
    21,22,23,24,25 * 5,9,12,15
    Sugar
    Sugar
    0 percent target mRNA inhibition
    23449220
    SM2440
    GGAUACUGCCAAUCUCUAGGUUUUU
    CCUAGAGAUUGGCAGUAUCCAAAAA
    Deoxyadenine* Mismatch
    Deoxyadenine* Mismatch
    21,22,23,24,25 * 6,9,12,16
    21,22,23,24,25 * 5,9,12,15
    Sugar
    Sugar
    0 percent target mRNA inhibition
    23449220
    SM2446
    GGAUACUGCCAAUCUCUAGGUUUUU
    CCUAGAGAUUGGCAGUAUCCAAAAA
    Deoxyadenine* Mismatch
    Deoxyadenine* Mismatch
    21,22,23,24,25 * 6,9,12,16
    21,22,23,24,25 * 5,9,12,15
    Sugar
    Sugar
    5 percent target mRNA inhibition
    23449220