Browse By

Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for Locked nucleic acid* Methylcytosine are 4
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM3071	CUUACGCUGAGUACUUCGATT TCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid* Methylcytosine	0 2,20,21 * 1	0 Sugar	85 percent target mRNA inhibition	15653644
SM3078	CUUACGCUGAGUACUUCGATT TCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid* Methylcytosine	0 9,20,21 * 1	0 Sugar	91 percent target mRNA inhibition	15653644
SM3080	CUUACGCUGAGUACUUCGATT TCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid* Methylcytosine	0 11,20,21 * 1	0 Sugar	92 percent target mRNA inhibition	15653644
SM3083	CUUACGCUGAGUACUUCGATT TCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid* Methylcytosine	0 14,20,21 * 1	0 Sugar	56 percent target mRNA inhibition	15653644