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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 2-Aminoethyl are 193
Results from 50 - 75

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SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM0562	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGT	2-Aminoethyl 2-Aminopropoxymethyl* 2-Deoxy	19 18,19 * 21	Sugar Sugar	6 percent target mRNA inhibition	19282453
SM0563	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGT	2-Aminoethyl 2-Aminopropoxymethyl* 2-Deoxy	5,19,20 18,19 * 21	Sugar Sugar	16.1 percent target mRNA inhibition	19282453
SM0587	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGC	2-Aminoethyl 2-Fluoro* 2-O-Methyl	18 1,3,5,7,9,11,13,15,17,19,21 * 2,4,6,8,10,12,14,16,18,20	Sugar Sugar	82.8 percent target mRNA inhibition	19282453
SM0606	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGC	2-Aminoethyl 2-Fluoro* 2-O-Methyl	20 1,3,5,7,9,11,13,15,17,19,21 * 2,4,6,8,10,12,14,16,18,20	Sugar Sugar	79.2 percent target mRNA inhibition	19282453
SM0607	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGC	2-Aminoethyl 2-Fluoro* 2-O-Methyl	19 1,3,5,7,9,11,13,15,17,19,21 * 2,4,6,8,10,12,14,16,18,20	Sugar Sugar	65.4 percent target mRNA inhibition	19282453
SM0608	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGC	2-Aminoethyl 2-Fluoro* 2-O-Methyl	5,19,20 1,3,5,7,9,11,13,15,17,19,21 * 2,4,6,8,10,12,14,16,18,20	Sugar Sugar	26.5 percent target mRNA inhibition	19282453
SM0632	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGC	2-Aminoethyl 2-Deoxy-2-N,4-C-Ethylene-Locked nucleic acid	18 3,18	Sugar Sugar	53.4 percent target mRNA inhibition	19282453
SM0651	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGC	2-Aminoethyl 2-Deoxy-2-N,4-C-Ethylene-Locked nucleic acid	20 3,18	Sugar Sugar	58.8 percent target mRNA inhibition	19282453
SM0652	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGC	2-Aminoethyl 2-Deoxy-2-N,4-C-Ethylene-Locked nucleic acid	19 3,18	Sugar Sugar	49.4 percent target mRNA inhibition	19282453
SM0653	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGC	2-Aminoethyl 2-Deoxy-2-N,4-C-Ethylene-Locked nucleic acid	5,19,20 3,18	Sugar Sugar	0.6 percent target mRNA inhibition	19282453
SM0677	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGC	2-Aminoethyl 2-Deoxy-2-N,4-C-Ethylene-Locked nucleic acid	18 4,18	Sugar Sugar	4.3 percent target mRNA inhibition	19282453
SM0696	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGC	2-Aminoethyl 2-Deoxy-2-N,4-C-Ethylene-Locked nucleic acid	20 4,18	Sugar Sugar	12.9 percent target mRNA inhibition	19282453
SM0697	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGC	2-Aminoethyl 2-Deoxy-2-N,4-C-Ethylene-Locked nucleic acid	19 4,18	Sugar Sugar	0 percent target mRNA inhibition	19282453
SM0698	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGC	2-Aminoethyl 2-Deoxy-2-N,4-C-Ethylene-Locked nucleic acid	5,19,20 4,18	Sugar Sugar	0 percent target mRNA inhibition	19282453
SM0722	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGC	2-Aminoethyl 2-Deoxy-2-N,4-C-Ethylene-Locked nucleic acid	18 3,4,18	Sugar Sugar	89.7 percent target mRNA inhibition	19282453
SM0741	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGC	2-Aminoethyl 2-Deoxy-2-N,4-C-Ethylene-Locked nucleic acid	20 3,4,18	Sugar Sugar	88.9 percent target mRNA inhibition	19282453
SM0742	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGC	2-Aminoethyl 2-Deoxy-2-N,4-C-Ethylene-Locked nucleic acid	19 3,4,18	Sugar Sugar	86.6 percent target mRNA inhibition	19282453
SM0743	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGC	2-Aminoethyl 2-Deoxy-2-N,4-C-Ethylene-Locked nucleic acid	5,19,20 3,4,18	Sugar Sugar	66.2 percent target mRNA inhibition	19282453
SM0767	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGC	2-Aminoethyl 2,4-Carbocyclic-Ethylene-bridged nucleic acid-Locked nucleic acid	18 3,18	Sugar Sugar	82.8 percent target mRNA inhibition	19282453
SM0786	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGC	2-Aminoethyl 2,4-Carbocyclic-Ethylene-bridged nucleic acid-Locked nucleic acid	20 3,18	Sugar Sugar	81.9 percent target mRNA inhibition	19282453
SM0787	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGC	2-Aminoethyl 2,4-Carbocyclic-Ethylene-bridged nucleic acid-Locked nucleic acid	19 3,18	Sugar Sugar	78.6 percent target mRNA inhibition	19282453
SM0788	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGC	2-Aminoethyl 2,4-Carbocyclic-Ethylene-bridged nucleic acid-Locked nucleic acid	5,19,20 3,18	Sugar Sugar	38.6 percent target mRNA inhibition	19282453
SM0812	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGC	2-Aminoethyl 2,4-Carbocyclic-Ethylene-bridged nucleic acid-Locked nucleic acid	18 4,18	Sugar Sugar	80.8 percent target mRNA inhibition	19282453
SM0831	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGC	2-Aminoethyl 2,4-Carbocyclic-Ethylene-bridged nucleic acid-Locked nucleic acid	20 4,18	Sugar Sugar	76.6 percent target mRNA inhibition	19282453
SM0832	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGC	2-Aminoethyl 2,4-Carbocyclic-Ethylene-bridged nucleic acid-Locked nucleic acid	19 4,18	Sugar Sugar	45 percent target mRNA inhibition	19282453



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