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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 2-Fluororibose* Phosphorothioate are 2
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM4804	GGAUCAUCUCAAGUCUUACTT GUAAGACUUGAGAUGAUCCTT	2-Fluororibose* Phosphorothioate 2-Fluororibose* Phosphorothioate	4,5,7,8,9,10,14,15,16,17,19 * 20 4,5,7,8,9,10,14,15,16,17,19 * 20	Sugar Sugar	IC-50 = 0.0074 nM for target mRNA	WO2014022739A3
SM4813	GGAUCAUCUCAAGUCUUACTT GUAAGACUUGAGAUGAUCCTT	2-Fluororibose* Phosphorothioate 2-Fluororibose* Xylo-3-fluororibose* Phosphorothioate	4,5,7,8,9,10,14,15,16,17,19 * 20 4,7,8,9,10,15,16,17,19 * 5,14 * 20	Sugar Sugar	NA	WO2014022739A3