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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


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• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for Hexitol nucleic acid* 2-Deoxy are 144
Results from 0 - 25

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SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM0010	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGC	Hexitol nucleic acid* 2-Deoxy 2-O-Methyl	1,2,3,18,19,20 * 21 2	Sugar Sugar	84 percent target mRNA inhibition	19282453
SM0011	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGC	Hexitol nucleic acid* 2-Deoxy 2-O-Methyl	5,8,11,14 * 21 2	Sugar Sugar	38 percent target mRNA inhibition	19282453
SM0012	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGC	Hexitol nucleic acid* 2-Deoxy 2-O-Methyl	5,8,11,14,19,20 * 21 2	Sugar Sugar	44.7 percent target mRNA inhibition	19282453
SM0056	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGCU	Hexitol nucleic acid* 2-Deoxy 2-O-Methyl* 2-Aminoethyl	1,2,3,18,19,20 * 21 1 * 21	Sugar Sugar	84 percent target mRNA inhibition	19282453
SM0057	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGCU	Hexitol nucleic acid* 2-Deoxy 2-O-Methyl* 2-Aminoethyl	5,8,11,14 * 21 1 * 21	Sugar Sugar	42 percent target mRNA inhibition	19282453
SM0058	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGCU	Hexitol nucleic acid* 2-Deoxy 2-O-Methyl* 2-Aminoethyl	5,8,11,14,19,20 * 21 1 * 21	Sugar Sugar	75 percent target mRNA inhibition	19282453
SM0101	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGCU	Hexitol nucleic acid* 2-Deoxy 2-O-Methyl* 2-Cyanoethyl	1,2,3,18,19,20 * 21 1 * 18	Sugar Sugar	57.2 percent target mRNA inhibition	19282453
SM0102	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGCU	Hexitol nucleic acid* 2-Deoxy 2-O-Methyl* 2-Cyanoethyl	5,8,11,14 * 21 1 * 18	Sugar Sugar	34.7 percent target mRNA inhibition	19282453
SM0103	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGCU	Hexitol nucleic acid* 2-Deoxy 2-O-Methyl* 2-Cyanoethyl	5,8,11,14,19,20 * 21 1 * 18	Sugar Sugar	51.2 percent target mRNA inhibition	19282453
SM0146	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGC	Hexitol nucleic acid* 2-Deoxy Altritol nucleic acid	1,2,3,18,19,20 * 21 1,2	Sugar Sugar	61.8 percent target mRNA inhibition	19282453
SM0147	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGC	Hexitol nucleic acid* 2-Deoxy Altritol nucleic acid	5,8,11,14 * 21 1,2	Sugar Sugar	40 percent target mRNA inhibition	19282453
SM0148	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGC	Hexitol nucleic acid* 2-Deoxy Altritol nucleic acid	5,8,11,14,19,20 * 21 1,2	Sugar Sugar	55.4 percent target mRNA inhibition	19282453
SM0191	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGCU	Hexitol nucleic acid* 2-Deoxy Altritol nucleic acid	1,2,3,18,19,20 * 21 20,21	Sugar Sugar	88.8 percent target mRNA inhibition	19282453
SM0192	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGCU	Hexitol nucleic acid* 2-Deoxy Altritol nucleic acid	5,8,11,14 * 21 20,21	Sugar Sugar	81 percent target mRNA inhibition	19282453
SM0193	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGCU	Hexitol nucleic acid* 2-Deoxy Altritol nucleic acid	5,8,11,14,19,20 * 21 20,21	Sugar Sugar	87.2 percent target mRNA inhibition	19282453
SM0236	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGCU	Hexitol nucleic acid* 2-Deoxy Altritol nucleic acid	1,2,3,18,19,20 * 21 5,8,11,14,17,20	Sugar Sugar	19.7 percent target mRNA inhibition	19282453
SM0237	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGCU	Hexitol nucleic acid* 2-Deoxy Altritol nucleic acid	5,8,11,14 * 21 5,8,11,14,17,20	Sugar Sugar	2.1 percent target mRNA inhibition	19282453
SM0238	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGCU	Hexitol nucleic acid* 2-Deoxy Altritol nucleic acid	5,8,11,14,19,20 * 21 5,8,11,14,17,20	Sugar Sugar	6.6 percent target mRNA inhibition	19282453
SM0281	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGCU	Hexitol nucleic acid* 2-Deoxy Altritol nucleic acid	1,2,3,18,19,20 * 21 3,6,14,18,20,21	Sugar Sugar	77 percent target mRNA inhibition	19282453
SM0282	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGCU	Hexitol nucleic acid* 2-Deoxy Altritol nucleic acid	5,8,11,14 * 21 3,6,14,18,20,21	Sugar Sugar	30.7 percent target mRNA inhibition	19282453
SM0283	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGCU	Hexitol nucleic acid* 2-Deoxy Altritol nucleic acid	5,8,11,14,19,20 * 21 3,6,14,18,20,21	Sugar Sugar	36.6 percent target mRNA inhibition	19282453
SM0326	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGT	Hexitol nucleic acid* 2-Deoxy Hexitol nucleic acid* 2-Deoxy	1,2,3,18,19,20 * 21 18,19,20 * 21	Sugar Sugar	84.6 percent target mRNA inhibition	19282453
SM0327	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGT	Hexitol nucleic acid* 2-Deoxy Hexitol nucleic acid* 2-Deoxy	5,8,11,14 * 21 18,19,20 * 21	Sugar Sugar	48.7 percent target mRNA inhibition	19282453
SM0328	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGT	Hexitol nucleic acid* 2-Deoxy Hexitol nucleic acid* 2-Deoxy	5,8,11,14,19,20 * 21 18,19,20 * 21	Sugar Sugar	74.2 percent target mRNA inhibition	19282453
SM0371	GACGUAAACGGCCACAAGUUT ACUUGUGGCCGUUUACGUCGT	Hexitol nucleic acid* 2-Deoxy Hexitol nucleic acid* 2-Deoxy	1,2,3,18,19,20 * 21 2,18,19,20 * 21	Sugar Sugar	77.4 percent target mRNA inhibition	19282453



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