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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for Locked nucleic acid* Phosphate are 2
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM4714	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	Locked nucleic acid* Phosphate Locked nucleic acid	2 * 1 1,2	Sugar Sugar	17 percent target mRNA inhibition	EP2548962A1
SM4719	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	Locked nucleic acid* Phosphate Locked nucleic acid	2 * 1 1,2	Sugar Sugar	49 percent target mRNA inhibition	EP2548962A1