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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
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  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for Palmitic acid* 2-Deoxyribonucleotide are 4
    Results from 0 - 25
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM4463
    UCCUACAGCACAACAAAUGUG
    CAUUUGUUGUGCUGUAGGATT
    Palmitic acid* 2-Deoxyribonucleotide
    2-Deoxyribonucleotide
    1 * 20,21
    20,21
    Phosphate; Sugar
    Sugar
    90 percent target mRNA inhibition
    21985606
    SM4469
    UCCUACAGCACAACAAAUGUG
    CAUUUGUUGUGCUGUAGGAAG
    Palmitic acid* 2-Deoxyribonucleotide
    2-Deoxyribonucleotide
    1 * 20,21
    20,21
    Phosphate; Sugar
    Sugar
    73 percent target mRNA inhibition
    21985606
    SM4475
    UCCUACAGCACAACAAAUGUG
    CAUUUGUUGUGCUGUAGGAAG
    Palmitic acid* 2-Deoxyribonucleotide
    2-Deoxyribonucleotide
    1 * 20,21
    20,21
    Phosphate; Sugar
    Sugar
    18 percent target mRNA inhibition
    21985606
    SM4481
    UCCUACAGCACAACAAAUGUG
    CAUUUGUUGUGCUGUAGGAAG
    Palmitic acid* 2-Deoxyribonucleotide
    2-Deoxyribonucleotide
    1 * 20,21
    20,21
    Phosphate; Sugar
    Sugar
    6 percent target mRNA inhibition
    21985606