Browse By

Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for Triazole-linked nucleic acid* Cholesterol are 7
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM4384	CUUACGCUGAGUACUUCGACU UCGAAGUACUCAGCGUAAGTT	Triazole-linked nucleic acid* Cholesterol 2-Deoxythymidine	20 * 21 20,21	Phosphate ; Base Sugar	85 percent target mRNA inhibition	25699137
SM4399	CUUACGCUGAGUACUUCGACU UCGAAGUACUCAGCGUAAGTT	Triazole-linked nucleic acid* Cholesterol 2-Deoxythymidine	20 * 21 20,21	Phosphate ; Base Sugar	95 percent target mRNA inhibition	25699137
SM4406	GUGAAGUCAACAUGCCUGCCU GCAGGCAUGUUGACUUCACTT	Triazole-linked nucleic acid* Cholesterol 2-Deoxythymidine	20 * 21 20,21	Phosphate ; Base Sugar	76 percent target mRNA inhibition	25699137
SM4413	GUGAAGUCAACAUGCCUGCCU GCAGGCAUGUUGACUUCACTT	Triazole-linked nucleic acid* Cholesterol 2-Deoxythymidine	20 * 21 20,21	Phosphate ; Base Sugar	10 percent target mRNA inhibition	25699137
SM4417	CUUACGCUGAGUACUUCGACU UCGAAGUACUCAGCGUAAGTT	Triazole-linked nucleic acid* Cholesterol 2-Deoxythymidine	20 * 21 20,21	Phosphate ; Base Sugar	30 percent target mRNA inhibition	25699137
SM4421	CUUACGCUGAGUACUUCGACU UCGAAGUACUCAGCGUAAGTT	Triazole-linked nucleic acid* Cholesterol 2-Deoxythymidine	20 * 21 20,21	Phosphate ; Base Sugar	82 percent target mRNA inhibition	25699137
SM4425	CUUACGCUGAGUACUUCGACU UCGAAGUACUCAGCGUAAGTT	Triazole-linked nucleic acid* Cholesterol 2-Deoxythymidine	20 * 21 20,21	Phosphate ; Base Sugar	84 percent target mRNA inhibition	25699137