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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
  • By modification in sense strand

  • By modification position in sense strand

  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for 5-Fluoro-2-Deoxyuridine are 6
    Results from 0 - 25
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM2427
    GGAUAUUGUCAGUCUUUAGGAAAAA
    CCUAAAGACUGACAAUAUCCUUUUU
    Deoxyadenine
    5-Fluoro-2-Deoxyuridine
    21,22,23,24,25
    21,22,23,24,25
    Sugar
    Sugar
    31 percent target mRNA inhibition
    23449220
    SM2428
    GGAUAUUGUCAGUCUUUAGGUUUUU
    CCUAAAGACUGACAAUAUCCUUUUU
    5-Fluoro-2-Deoxyuridine
    5-Fluoro-2-Deoxyuridine
    21,22,23,24,25
    21,22,23,24,25
    Sugar
    Sugar
    NA
    23449220
    SM2438
    GGAUAUUGUCAGUCUUUAGGAAAAA
    CCUAAAGACUGACAAUAUCCUUUUU
    Deoxyadenine
    5-Fluoro-2-Deoxyuridine
    21,22,23,24,25
    21,22,23,24,25
    Sugar
    Sugar
    68 percent target mRNA inhibition
    23449220
    SM2439
    GGAUAUUGUCAGUCUUUAGGUUUUU
    CCUAAAGACUGACAAUAUCCUUUUU
    5-Fluoro-2-Deoxyuridine
    5-Fluoro-2-Deoxyuridine
    21,22,23,24,25
    21,22,23,24,25
    Sugar
    Sugar
    35 percent target mRNA inhibition
    23449220
    SM2444
    GGAUAUUGUCAGUCUUUAGGAAAAA
    CCUAAAGACUGACAAUAUCCUUUUU
    Deoxyadenine
    5-Fluoro-2-Deoxyuridine
    21,22,23,24,25
    21,22,23,24,25
    Sugar
    Sugar
    54 percent target mRNA inhibition
    23449220
    SM2445
    GGAUAUUGUCAGUCUUUAGGUUUUU
    CCUAAAGACUGACAAUAUCCUUUUU
    5-Fluoro-2-Deoxyuridine
    5-Fluoro-2-Deoxyuridine
    21,22,23,24,25
    21,22,23,24,25
    Sugar
    Sugar
    60 percent target mRNA inhibition
    23449220