| Field | Sense | Antisense |
| siRNA chemical modification | 12-[(2,3,4,6-Tetra-O-methyl-b-D-glucopyranosyloxy)]dodecyl (2-cyanoethyl) (N,N-diisopropyl) phosphoramidite derivative | 0 |
| siRNA modification types | 1 | 0 |
| Overall number of modifications | 1 | 0 |
| Position of modifications | 1 | 0 |
| Modification on sugar or base or phosphate | Phosphate | 0 |
| SMILES (Click to view structure & nomenclature) |
COC1OC(OCCCCCCCCCCCCOP(O)(=O)OCCCCC(=O)NCC(CNC(=O)CCCCOP(O)(=O)OCCCCCCCCCCCCOC2OC(OC)C(OC)C(OC)C2OC)OP(O)(O)=O)C(OC)C(OC)C1OC |
- |
| siRNA Sequence | AUCUGAAGAAGGAGAAAAATT | UUUUUCUCCUUCUUCAGAUTT |
| siRNA length base-pair | 21 | 21 |
| siRNA name in paper | 3 | 3 |
| Biological activity | 79 percent target mRNA inhibition | |
| Experiment used to check activity | Luciferase reporter assay | |
| Melting temperature (oC) | NA | |
| Target gene | Luciferase gene | |
| siRNA concentration | 0.8 nM | |
| Cell or Organism used | HeLa and HuH-cells | |
| Transfection method | Lipofectamine 2007 | |
| Duration after transfection | 24 Hours | |
| Article title | Synthesis, RNAi activity and nuclease-resistant properties of apolar carbohydrates siRNA conjugates |
|
| Reference | 23764303 | |