| Field | Sense | Antisense |
| siRNA chemical modification | 2-O-Methyl | 2-O-Methyl |
| siRNA modification types | 1 | 1 |
| Overall number of modifications | 10 | 10 |
| Position of modifications | 1,3,5,7,9,11,13,15,17,19 | 1,3,5,7,9,11,13,15,17,19 |
| Modification on sugar or base or phosphate | Sugar | Sugar |
| SMILES (Click to view structure & nomenclature) |
COC1C(O)OC(CO)C1O |
COC1C(O)OC(CO)C1O |
| siRNA Sequence | AAUUCCAGUGGUUCAUUCC | GGAAUGAACCACUGGAAUU |
| siRNA length base-pair | 19 | 19 |
| siRNA name in paper | p110beta V6 | p110beta V6 |
| Biological activity | NA | |
| Experiment used to check activity | Real-time PCR | |
| Melting temperature (oC) | NA | |
| Target gene | p110beta gene | |
| siRNA concentration | 1 to 40 nM | |
| Cell or Organism used | HeLa cells | |
| Transfection method | Oligofectamine (Invitrogen) | |
| Duration after transfection | 48 Hours | |
| Article title | Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells |
|
| Reference | 12771196 | |