| Field | Sense | Antisense |
| siRNA chemical modification | Peptide nucleic acids | Peptide nucleic acids |
| siRNA modification types | 1 | 1 |
| Overall number of modifications | 1 | 1 |
| Position of modifications | 21 | 21 |
| Modification on sugar or base or phosphate | Phosphate | Phosphate |
| SMILES (Click to view structure & nomenclature) |
CNC(=O)CN(C)C(C)=O |
CNC(=O)CN(C)C(C)=O |
| siRNA Sequence | UCGAAGUAUUCCGCGUACGTT | CGUACGCGGAAUACUUCGATT |
| siRNA length base-pair | 21 | 21 |
| siRNA name in paper | D | D |
| Biological activity | 75 percent target mRNA inhibition | |
| Experiment used to check activity | Dual luciferase reporter assay | |
| Melting temperature (oC) | NA | |
| Target gene | Luciferase gene | |
| siRNA concentration | 10 nM | |
| Cell or Organism used | HeLa cells | |
| Transfection method | Cationic liposomes | |
| Duration after transfection | 48 Hours | |
| Article title | RNA interference in mammalia cells by RNA-3'-PNA chimeras |
|
| Reference | 19325750 | |