SM2712 Chemically modified siRNA information

Field Sense Antisense
siRNA chemical modification 0 Methyl
siRNA modification types 0 1
Overall number of modifications 0 1
Position of modifications 0 21
Modification on sugar or base or phosphate 0 Sugar
SMILES
(Click to view structure & nomenclature)
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CC1C(O)COC1CO



siRNA Sequence UCGAAGUAUUCCGCGUACGTT CGUACGCGGAAUACUUCGATT
siRNA length base-pair 21 21
siRNA name in paper ME ME
Biological activity 78 percent target mRNA inhibition
Experiment used to check activity Dual luciferase reporter assay
Melting temperature (oC) NA
Target gene Luciferase gene
siRNA concentration 0.032 nM
Cell or Organism used HeLa cells
Transfection method NA
Duration after transfection 24 Hours
Article title Modified siRNAs for the study of the PAZ domain
Reference20485810