SM2724 Chemically modified siRNA information

Field Sense Antisense
siRNA chemical modification 0 Trifluoromethylbenzene
siRNA modification types 0 1
Overall number of modifications 0 1
Position of modifications 0 21
Modification on sugar or base or phosphate 0 Sugar
SMILES
(Click to view structure & nomenclature)
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FC(F)(F)C1=CC=CC=C1



siRNA Sequence UCGAAGUAUUCCGCGUACGTT CGUACGCGGAAUACUUCGATT
siRNA length base-pair 21 21
siRNA name in paper CF3 CF3
Biological activity 69 percent target mRNA inhibition
Experiment used to check activity Dual luciferase reporter assay
Melting temperature (oC) NA
Target gene Luciferase gene
siRNA concentration 0.32 nM
Cell or Organism used SH-SY5Y cells
Transfection method NA
Duration after transfection 24 Hours
Article title Modified siRNAs for the study of the PAZ domain
Reference20485810