Field | Sense | Antisense |
siRNA chemical modification | 0 | Trifluoromethylbenzene |
siRNA modification types | 0 | 1 |
Overall number of modifications | 0 | 1 |
Position of modifications | 0 | 21 |
Modification on sugar or base or phosphate | 0 | Sugar |
SMILES (Click to view structure & nomenclature) |
- |
FC(F)(F)C1=CC=CC=C1 |
siRNA Sequence | UCGAAGUAUUCCGCGUACGTT | CGUACGCGGAAUACUUCGATT |
siRNA length base-pair | 21 | 21 |
siRNA name in paper | CF3 | CF3 |
Biological activity | 69 percent target mRNA inhibition | |
Experiment used to check activity | Dual luciferase reporter assay | |
Melting temperature (oC) | NA | |
Target gene | Luciferase gene | |
siRNA concentration | 0.32 nM | |
Cell or Organism used | SH-SY5Y cells | |
Transfection method | NA | |
Duration after transfection | 24 Hours | |
Article title | Modified siRNAs for the study of the PAZ domain |
|
Reference | 20485810 |