Field | Sense | Antisense |
siRNA chemical modification | Tricyclodeoxyribonucleic acid | 0 |
siRNA modification types | 1 | 0 |
Overall number of modifications | 5 | 0 |
Position of modifications | 2,5,7,20,21 | 0 |
Modification on sugar or base or phosphate | Sugar | 0 |
SMILES (Click to view structure & nomenclature) |
OC1CCC2(O)CCOC12 |
- |
siRNA Sequence | GCAGCACGACUUCUUCAAGTT | CUUGAAGAAGUCGUGCUGCTT |
siRNA length base-pair | 21 | 21 |
siRNA name in paper | siYY5 | siYY5 |
Biological activity | 79 percent target mRNA inhibition | |
Experiment used to check activity | FACS | |
Melting temperature (oC) | NA | |
Target gene | GFP gene | |
siRNA concentration | 50 nM | |
Cell or Organism used | HeLa cells | |
Transfection method | Lipofectamine | |
Duration after transfection | 48 Hours | |
Article title | Synthesis and silencing properties of siRNAs possessing lipophilic groups at their 3'-termini |
|
Reference | 18776474 |