SM3358 Chemically modified siRNA information

Field Sense Antisense
siRNA chemical modification 0 2-Deoxy-2-fluorouridine
siRNA modification types 0 1
Overall number of modifications 0 2
Position of modifications 0 3,20
Modification on sugar or base or phosphate 0 Sugar
SMILES
(Click to view structure & nomenclature)
-



OCC1OC(C(F)C1O)N1C=CC(=O)NC1=O



siRNA Sequence AGACGAGCUGAGCGAGAAGTT TTUCUGCUCGACUCGCUCUUC
siRNA length base-pair 21 21
siRNA name in paper F3 F3
Biological activity NA
Experiment used to check activity NA
Melting temperature (oC) 80
Target gene Human Caveolin-1 gene
siRNA concentration 200 nM
Cell or Organism used HeLa cells
Transfection method Oligofectamine (Invitrogen)
Duration after transfection 10-14 Hours
Article title RNA interference in mammalian cells by chemically-modified RNA
Reference12834349