SM3360 Chemically modified siRNA information

Field Sense Antisense
siRNA chemical modification 2-Deoxy-2-fluorouridine 0
siRNA modification types 1 0
Overall number of modifications 1 0
Position of modifications 9 0
Modification on sugar or base or phosphate Sugar 0
SMILES
(Click to view structure & nomenclature)
OCC1OC(C(F)C1O)N1C=CC(=O)NC1=O



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siRNA Sequence AGACGAGCUGAGCGAGAAGTT TTUCUGCUCGACUCGCUCUUC
siRNA length base-pair 21 21
siRNA name in paper F5 F5
Biological activity NA
Experiment used to check activity NA
Melting temperature (oC) 79
Target gene Human Caveolin-1 gene
siRNA concentration 200 nM
Cell or Organism used HeLa cells
Transfection method Oligofectamine (Invitrogen)
Duration after transfection 10-14 Hours
Article title RNA interference in mammalian cells by chemically-modified RNA
Reference12834349