| Field | Sense | Antisense |
| siRNA chemical modification | Altritol nucleic acid | Altritol nucleic acid |
| siRNA modification types | 1 | 1 |
| Overall number of modifications | 4 | 3 |
| Position of modifications | 3,4,20,21 | 18,19,20 |
| Modification on sugar or base or phosphate | Sugar | Sugar |
| SMILES (Click to view structure & nomenclature) |
OCC12COC(CO1)C2O |
OCC12COC(CO1)C2O |
| siRNA Sequence | ACCUUGAGGCAUACUUCAATT | UUGAAGUAUGCCUCAAGGUCG |
| siRNA length base-pair | 21 | 21 |
| siRNA name in paper | siRNA3 | siRNA3 |
| Biological activity | NA | |
| Experiment used to check activity | Real-time PCR | |
| Melting temperature (oC) | NA | |
| Target gene | HBsAg gene | |
| siRNA concentration | 10 nM | |
| Cell or Organism used | Huh7 cells | |
| Transfection method | Lipofectamine 2000 | |
| Duration after transfection | 48 Hours | |
| Article title | Inhibition of hepatitis B virus replication in vivo using lipoplexes containing altritol-modified antiviral siRNAs |
|
| Reference | 21687523 | |