| Field | Sense | Antisense |
| siRNA chemical modification | Methyleneamide | Methyleneamide |
| siRNA modification types | 1 | 1 |
| Overall number of modifications | 1 | 1 |
| Position of modifications | 20 | 1 |
| Modification on sugar or base or phosphate | Sugar | Sugar |
| SMILES (Click to view structure & nomenclature) |
NC(=O)CC1C(O)COC1CO |
NC(=O)CC1C(O)COC1CO |
| siRNA Sequence | CUUACGCUGAGUACUUCGAUU | UUGAAUGCGACUCAUGAAGCU |
| siRNA length base-pair | 21 | 21 |
| siRNA name in paper | siRNA-ad1 | siRNA-ad1 |
| Biological activity | NA | |
| Experiment used to check activity | NA | |
| Melting temperature (oC) | Increased (0.8) | |
| Target gene | Luciferase gene | |
| siRNA concentration | 20 nM | |
| Cell or Organism used | A549 cells | |
| Transfection method | NA | |
| Duration after transfection | NA | |
| Article title | Solid-phase synthesis of modified RNAs containing amide-linked oligoribonucleosides at their 3'-end and their application to siRNA |
|
| Reference | 18066804 | |