SM3393 Chemically modified siRNA information

Field Sense Antisense
siRNA chemical modification 2-O-Methyl 0
siRNA modification types 1 0
Overall number of modifications 19 0
Position of modifications 1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19 0
Modification on sugar or base or phosphate Sugar 0
SMILES
(Click to view structure & nomenclature)
COC1C(O)OC(CO)C1O



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siRNA Sequence TCTCTGCGGTGGTTGGCAT AGAGACGCCACCAACCGUA
siRNA length base-pair 19 19
siRNA name in paper scL-siRNA scL-siRNA
Biological activity NA
Experiment used to check activity Real-time PCR
Melting temperature (oC) NA
Target gene HER-2 gene
siRNA concentration 100 nM
Cell or Organism used PANC-1 cells
Transfection method Injection
Duration after transfection 6 Hours
Article title Materializing the potential of small interfering RNA via a tumor-targeting nanodelivery system
Reference17409398