| Field | Sense | Antisense |
| siRNA chemical modification | 2-O-Methyl | 2-O-Methyl |
| siRNA modification types | 1 | 1 |
| Overall number of modifications | 19 | 19 |
| Position of modifications | 1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19 | 1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19 |
| Modification on sugar or base or phosphate | Sugar | Sugar |
| SMILES (Click to view structure & nomenclature) |
COC1C(O)OC(CO)C1O |
COC1C(O)OC(CO)C1O |
| siRNA Sequence | CCACCACAGCUAGAACUUA | UAAGUUCUAGCUGUGGUGG |
| siRNA length base-pair | 19 | 19 |
| siRNA name in paper | PTEN | PTEN |
| Biological activity | NA | |
| Experiment used to check activity | Real-time PCR | |
| Melting temperature (oC) | NA | |
| Target gene | Human PTEN gene | |
| siRNA concentration | 10 nM | |
| Cell or Organism used | PC-3, NIH3T3 cells | |
| Transfection method | Injection | |
| Duration after transfection | 48 Hours | |
| Article title | RNA interference in the mouse vascular endothelium by systemic administration of siRNA-lipoplexes for cancer therapy |
|
| Reference | 16625242 | |