| Field | Sense | Antisense |
| siRNA chemical modification | Cholesterol | 0 |
| siRNA modification types | 1 | 0 |
| Overall number of modifications | 1 | 0 |
| Position of modifications | 1 | 0 |
| Modification on sugar or base or phosphate | Phosphate | 0 |
| SMILES (Click to view structure & nomenclature) |
CC(C)CCCC(C)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C |
- |
| siRNA Sequence | GGCCUUUCACUACUCCUACGA | GUAGGAGUAGUGAAAGGCCAG |
| siRNA length base-pair | 21 | 21 |
| siRNA name in paper | Chol-siLuc | Chol-siLuc |
| Biological activity | 42 percent target mRNA inhibition | |
| Experiment used to check activity | Real-time PCR | |
| Melting temperature (oC) | NA | |
| Target gene | Renilla luciferase | |
| siRNA concentration | 100 nM | |
| Cell or Organism used | HeLa cells | |
| Transfection method | Absence of Lipofectamine 2000 | |
| Duration after transfection | 48 Hours | |
| Article title | Palmitic acid-conjugated 21-nucleotide siRNA enhances gene-silencing activity |
|
| Reference | 21985606 | |