| Field | Sense | Antisense |
| siRNA chemical modification | 1-Aminohexane* 2-Deoxyribonucleotide* N-hexylhexadecanamide | 1-Aminohexane |
| siRNA modification types | 3 | 1 |
| Overall number of modifications | 4 | 1 |
| Position of modifications | 1 * 24,25 * 25 | 1 |
| Modification on sugar or base or phosphate | Phosphate; Sugar | Phosphate |
| SMILES (Click to view structure & nomenclature) |
CCCCCCN OCC1OCCC1O CCCCCCCCCCCCCCCC(=O)NCCCCCC |
CCCCCCN |
| siRNA Sequence | GGCCUUUCACUACUCCUACGAGCAC | GUGCUCGUAGGAGUAGUGAAAGGCCAG |
| siRNA length base-pair | 25 | 27 |
| siRNA name in paper | C16 DsiRNA | DsiRNA-I |
| Biological activity | 82 percent target mRNA inhibition | |
| Experiment used to check activity | Luciferase gene reporter assay | |
| Melting temperature (oC) | NA | |
| Target gene | Renilla luciferase gene | |
| siRNA concentration | 0.2 nM | |
| Cell or Organism used | HeLa cells | |
| Transfection method | Lipofectamine 2000 | |
| Duration after transfection | 48 Hours | |
| Article title | Amino-modified and lipid-conjugated dicer-substrate siRNA enhances RNAi efficacy |
|
| Reference | 22236254 | |